Perigenual anterior cingulate morphology covaries with perceived social standing. Export

@article{citeulike:6101154, abstract = {Low socioeconomic status (SES) increases the risk for developing psychiatric and chronic medical disorders. A stress-related pathway by which low SES may affect mental and physical health is through the perception of holding a low social standing, termed low subjective social status. This proposal implicates overlapping brain regions mediating stress reactivity and socioemotional behaviors as neuroanatomical substrates that could plausibly link subjective social status to health-related outcomes. In a test of this proposal, we used a computational structural neuroimaging method (voxel-based morphometry) in a healthy community sample to examine the relationships between reports of subjective social status and regional gray matter volume. Results showed that after accounting for potential demographic confounds, subclinical depressive symptoms, dispositional forms of negative emotionality and conventional indicators of SES, self-reports of low subjective social status uniquely covaried with reduced gray matter volume in the perigenual area of the anterior cingulate cortex (pACC)-a brain region involved in experiencing emotions and regulating behavioral and physiological reactivity to psychosocial stress. The pACC may represent a neuroanatomical substrate by which perceived social standing relates to mental and physical health.}, author = {Gianaros, Peter J. and Horenstein, Jeffrey A. and Cohen, Sheldon and Matthews, Karen A. and Brown, Sarah M. and Flory, Janine D. and Critchley, Hugo D. and Manuck, Stephen B. and Hariri, Ahmad R.}, citeulike-article-id = {6101154}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/scan/nsm013}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18418472}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18418472}, doi = {10.1093/scan/nsm013}, issn = {1749-5024}, journal = {Social cognitive and affective neuroscience}, keywords = {brain, chronic, markers, morphology, pathways, socioeconomic, status, stress}, month = {September}, number = {3}, pages = {161--173}, posted-at = {2009-11-12 10:35:30}, priority = {2}, title = {Perigenual anterior cingulate morphology covaries with perceived social standing.}, url = {http://dx.doi.org/10.1093/scan/nsm013}, volume = {2}, year = {2007} }

TY - JOUR ID - citeulike:6101154 L3 - citeulike-article-id:6101154 N2 - Low socioeconomic status (SES) increases the risk for developing psychiatric and chronic medical disorders. A stress-related pathway by which low SES may affect mental and physical health is through the perception of holding a low social standing, termed low subjective social status. This proposal implicates overlapping brain regions mediating stress reactivity and socioemotional behaviors as neuroanatomical substrates that could plausibly link subjective social status to health-related outcomes. In a test of this proposal, we used a computational structural neuroimaging method (voxel-based morphometry) in a healthy community sample to examine the relationships between reports of subjective social status and regional gray matter volume. Results showed that after accounting for potential demographic confounds, subclinical depressive symptoms, dispositional forms of negative emotionality and conventional indicators of SES, self-reports of low subjective social status uniquely covaried with reduced gray matter volume in the perigenual area of the anterior cingulate cortex (pACC)-a brain region involved in experiencing emotions and regulating behavioral and physiological reactivity to psychosocial stress. The pACC may represent a neuroanatomical substrate by which perceived social standing relates to mental and physical health. IS - 3 JF - Social cognitive and affective neuroscience SN - 1749-5024 EP - 173 TI - Perigenual anterior cingulate morphology covaries with perceived social standing. VL - 2 SP - 161 KW - brain KW - chronic KW - markers KW - morphology KW - pathways KW - socioeconomic KW - status KW - stress AU - Gianaros, Peter AU - Horenstein, Jeffrey AU - Cohen, Sheldon AU - Matthews, Karen AU - Brown, Sarah AU - Flory, Janine AU - Critchley, Hugo AU - Manuck, Stephen AU - Hariri, Ahmad PY - 2007/09// UR - http://dx.doi.org/10.1093/scan/nsm013 ER -