Automatic segmentation of thalamic nuclei from diffusion tensor magnetic resonance imaging. Export

@article{wiegell+tuch-thalamus-segmentation, abstract = {The nuclei of the thalamus have traditionally been delineated by their distinct cyto/myeloarchitectural appearance on histology. Here, we show that diffusion tensor magnetic resonance imaging (DTI) can noninvasively resolve the major thalamic nuclei based on the characteristic fiber orientation of the corticothalamic/thalamocortical striations within each nucleus. Using an automatic clustering algorithm, we extracted the Talairach coordinates for the individual thalamic nuclei. The center-of-mass coordinates for the segmented nuclei were found to agree strongly with those obtained from a histological atlas. The ability to resolve thalamic nuclei with DTI will allow for morphometric analysis of specific nuclei and improved anatomical localization of functional activation in the thalamus.}, address = {Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Room 2301, Charlestown, MA 02129, USA. mette@nmr.mgh.harvard.edu}, author = {Wiegell, M. R. and Tuch, D. S. and Larsson, H. B. and Wedeen, V. J.}, citeulike-article-id = {246406}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12814588}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12814588}, issn = {1053-8119}, journal = {Neuroimage}, keywords = {anatomy, dti, pubmed, segmentation}, month = {June}, number = {2 Pt 1}, pages = {391--401}, posted-at = {2006-09-26 19:43:41}, priority = {2}, title = {Automatic segmentation of thalamic nuclei from diffusion tensor magnetic resonance imaging.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12814588}, volume = {19}, year = {2003} }

TY - JOUR ID - wiegell+tuch-thalamus-segmentation L3 - citeulike-article-id:246406 N2 - The nuclei of the thalamus have traditionally been delineated by their distinct cyto/myeloarchitectural appearance on histology. Here, we show that diffusion tensor magnetic resonance imaging (DTI) can noninvasively resolve the major thalamic nuclei based on the characteristic fiber orientation of the corticothalamic/thalamocortical striations within each nucleus. Using an automatic clustering algorithm, we extracted the Talairach coordinates for the individual thalamic nuclei. The center-of-mass coordinates for the segmented nuclei were found to agree strongly with those obtained from a histological atlas. The ability to resolve thalamic nuclei with DTI will allow for morphometric analysis of specific nuclei and improved anatomical localization of functional activation in the thalamus. IS - 2 Pt 1 JF - Neuroimage SN - 1053-8119 AD - Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Room 2301, Charlestown, MA 02129, USA. mette@nmr.mgh.harvard.edu EP - 401 TI - Automatic segmentation of thalamic nuclei from diffusion tensor magnetic resonance imaging. VL - 19 SP - 391 KW - anatomy KW - dti KW - pubmed KW - segmentation AU - Wiegell, MR AU - Tuch, DS AU - Larsson, HB AU - Wedeen, VJ PY - 2003/06// UR - http://view.ncbi.nlm.nih.gov/pubmed/12814588 ER -