Diffusion tensor imaging: concepts and applications. Export

@article{citeulike:796538, abstract = {The success of diffusion magnetic resonance imaging (MRI) is deeply rooted in the powerful concept that during their random, diffusion-driven displacements molecules probe tissue structure at a microscopic scale well beyond the usual image resolution. As diffusion is truly a three-dimensional process, molecular mobility in tissues may be anisotropic, as in brain white matter. With diffusion tensor imaging (DTI), diffusion anisotropy effects can be fully extracted, characterized, and exploited, providing even more exquisite details on tissue microstructure. The most advanced application is certainly that of fiber tracking in the brain, which, in combination with functional MRI, might open a window on the important issue of connectivity. DTI has also been used to demonstrate subtle abnormalities in a variety of diseases (including stroke, multiple sclerosis, dyslexia, and schizophrenia) and is currently becoming part of many routine clinical protocols. The aim of this article is to review the concepts behind DTI and to present potential applications.}, address = {Service Hospitalier Fr\'{e}d\'{e}ric Joliot, CEA, 91406 Orsay, France. lebihan@shfj.cea.fr}, author = {Le Bihan, D. and Mangin, J. F. and Poupon, C. and Clark, C. A. and Pappata, S. and Molko, N. and Chabriat, H.}, citeulike-article-id = {796538}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/11276097}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=11276097}, comment = {Full text: http://noodle.med.yale.edu/\~{}mjack/papers/bihan2001.pdf ---=note-separator=--- test}, issn = {1053-1807}, journal = {J Magn Reson Imaging}, keywords = {dti, neuroscience, pubmed}, month = {April}, number = {4}, pages = {534--546}, posted-at = {2006-09-19 14:46:46}, priority = {3}, title = {Diffusion tensor imaging: concepts and applications.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11276097}, volume = {13}, year = {2001} }

TY - JOUR ID - citeulike:796538 L3 - citeulike-article-id:796538 N2 - The success of diffusion magnetic resonance imaging (MRI) is deeply rooted in the powerful concept that during their random, diffusion-driven displacements molecules probe tissue structure at a microscopic scale well beyond the usual image resolution. As diffusion is truly a three-dimensional process, molecular mobility in tissues may be anisotropic, as in brain white matter. With diffusion tensor imaging (DTI), diffusion anisotropy effects can be fully extracted, characterized, and exploited, providing even more exquisite details on tissue microstructure. The most advanced application is certainly that of fiber tracking in the brain, which, in combination with functional MRI, might open a window on the important issue of connectivity. DTI has also been used to demonstrate subtle abnormalities in a variety of diseases (including stroke, multiple sclerosis, dyslexia, and schizophrenia) and is currently becoming part of many routine clinical protocols. The aim of this article is to review the concepts behind DTI and to present potential applications. IS - 4 JF - J Magn Reson Imaging SN - 1053-1807 AD - Service Hospitalier Frédéric Joliot, CEA, 91406 Orsay, France. lebihan@shfj.cea.fr EP - 546 TI - Diffusion tensor imaging: concepts and applications. VL - 13 SP - 534 KW - dti KW - neuroscience KW - pubmed N1 - Full text: http://noodle.med.yale.edu/~mjack/papers/bihan2001.pdf N1 - test AU - Le Bihan, D AU - Mangin, JF AU - Poupon, C AU - Clark, CA AU - Pappata, S AU - Molko, N AU - Chabriat, H PY - 2001/04// UR - http://view.ncbi.nlm.nih.gov/pubmed/11276097 ER -