A primer on diffusion tensor imaging of anatomical substructures. Export

@article{citeulike:853219, abstract = {In this article, the authors review the application of diffusion tensor (DT) magnetic resonance (MR) imaging to demonstrate anatomical substructures that cannot be resolved by conventional structural imaging. They review the physical basis of DT imaging and provide illustrative anatomical examples. The DT imaging technique measures the self-diffusion, or random thermal motion, of the endogenous water in nerve tissue. Because of the preferred diffusion of water molecules along the nerve fiber direction, DT imaging can measure the orientation of the neural fiber structure within each voxel of the MR image. The fiber orientation information yielded by DT imaging provides a new contrast mechanism that can be used to resolve images of anatomical substructures that cannot otherwise be visualized using conventional structural imaging. The authors illustrate how DT imaging can resolve individual pathways in the brainstem as well as individual nuclei of the thalamus and conclude by describing potential applications in neurosurgery.}, address = {Martinos Center for Biomedical Imaging, Massachusetts General Hospital, NMR Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.}, author = {DaSilva, A. F. and Tuch, D. S. and Wiegell, M. R. and Hadjikhani, N.}, citeulike-article-id = {853219}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/15355006}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=15355006}, day = {15}, issn = {1092-0684}, journal = {Neurosurg Focus}, keywords = {dti, neuroscience, pubmed, review, segmentation}, month = {July}, number = {1}, posted-at = {2006-09-21 16:55:38}, priority = {2}, title = {A primer on diffusion tensor imaging of anatomical substructures.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15355006}, volume = {15}, year = {2003} }

TY - JOUR ID - citeulike:853219 L3 - citeulike-article-id:853219 N2 - In this article, the authors review the application of diffusion tensor (DT) magnetic resonance (MR) imaging to demonstrate anatomical substructures that cannot be resolved by conventional structural imaging. They review the physical basis of DT imaging and provide illustrative anatomical examples. The DT imaging technique measures the self-diffusion, or random thermal motion, of the endogenous water in nerve tissue. Because of the preferred diffusion of water molecules along the nerve fiber direction, DT imaging can measure the orientation of the neural fiber structure within each voxel of the MR image. The fiber orientation information yielded by DT imaging provides a new contrast mechanism that can be used to resolve images of anatomical substructures that cannot otherwise be visualized using conventional structural imaging. The authors illustrate how DT imaging can resolve individual pathways in the brainstem as well as individual nuclei of the thalamus and conclude by describing potential applications in neurosurgery. IS - 1 JF - Neurosurg Focus SN - 1092-0684 AD - Martinos Center for Biomedical Imaging, Massachusetts General Hospital, NMR Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA. TI - A primer on diffusion tensor imaging of anatomical substructures. VL - 15 KW - dti KW - neuroscience KW - pubmed KW - review KW - segmentation AU - DaSilva, AF AU - Tuch, DS AU - Wiegell, MR AU - Hadjikhani, N PY - 2003/07/15/ UR - http://view.ncbi.nlm.nih.gov/pubmed/15355006 ER -