Facultative but persistent trans-generational immunity via the mother's eggs in bumblebees Export

@article{citeulike:2397445, abstract = {Summary It is widely acknowledged that a mother, and the maternal environment, can have a profound effect on the phenotype of her offspring [1]. For example, immunocompetent vertebrate mothers can pass on immune factors to their otherwise immune naive offspring [2]. Recently, it has also been demonstrated in invertebrates that maternal contact with pathogens and immune elicitors can have a positive impact on offspring resistance [3] and immune system components [4] and [5]. Here, using a cross-fostering design, we show that trans-generational immune priming in a social insect, similar to birds [2], takes place through factors in the eggs, with effects persisting into adult worker offspring. Additionally, eggs from immune-challenged mothers are imbued with increased internal antibacterial activity when they are laid.}, author = {Sadd, Ben M. and Schmid-Hempel, Paul}, citeulike-article-id = {2397445}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.cub.2007.11.007}, citeulike-linkout-1 = {http://www.sciencedirect.com/science/article/B6VRT-4RCG53V-D/2/af6027da7ff2a44742a372ce76bf2a5e}, day = {18}, doi = {10.1016/j.cub.2007.11.007}, journal = {Current Biology}, month = {December}, number = {24}, pages = {R1046--R1047}, posted-at = {2008-02-19 06:20:34}, priority = {5}, title = {Facultative but persistent trans-generational immunity via the mother's eggs in bumblebees}, url = {http://dx.doi.org/10.1016/j.cub.2007.11.007}, volume = {17}, year = {2007} }

TY - JOUR ID - citeulike:2397445 L3 - citeulike-article-id:2397445 N2 - Summary It is widely acknowledged that a mother, and the maternal environment, can have a profound effect on the phenotype of her offspring [1]. For example, immunocompetent vertebrate mothers can pass on immune factors to their otherwise immune naive offspring [2]. Recently, it has also been demonstrated in invertebrates that maternal contact with pathogens and immune elicitors can have a positive impact on offspring resistance [3] and immune system components [4] and [5]. Here, using a cross-fostering design, we show that trans-generational immune priming in a social insect, similar to birds [2], takes place through factors in the eggs, with effects persisting into adult worker offspring. Additionally, eggs from immune-challenged mothers are imbued with increased internal antibacterial activity when they are laid. IS - 24 JF - Current Biology EP - R1047 TI - Facultative but persistent trans-generational immunity via the mother's eggs in bumblebees VL - 17 SP - R1046 AU - Sadd, Ben AU - Schmid-Hempel, Paul PY - 2007/12/18/ UR - http://dx.doi.org/10.1016/j.cub.2007.11.007 ER -