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Colloidal particle motion as a diagnostic of DNA conformational transitionsby: Philip C Nelson
(4 Oct 2007)
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AbstractTethered particle motion is an experimental technique to monitor conformational changes in single molecules of DNA in real time, by observing the position fluctuations of a micrometer-size particle attached to the DNA. This article reviews some recent work on theoretical problems inherent in the interpretation of TPM experiments, both in equilibrium and dynamical aspects.
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