One hundred years of positional information. Export

@article{citeulike:1467421, abstract = {One mechanism by which spatial patterns of cell differentiation could be specified during embryonic development and regeneration is based on positional information. Cells acquire a positional value with respect to boundaries and then interpret this in terms of a programme determined by their genetic constitution and developmental history. The signals and the molecular basis of such a system have both been rather well conserved. Recent work has shown that cells can respond to quite small differences in the concentrations of molecules whose concentration could provide positional information.}, address = {Department of Anatomy and Developmental Biology, University College, London, UK. Lwolpert@ucl.ac.uk}, author = {Wolpert, L.}, citeulike-article-id = {1467421}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/8855666}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=8855666}, issn = {0168-9525}, journal = {Trends Genet}, keywords = {cells, signalling}, month = {September}, number = {9}, pages = {359--364}, posted-at = {2007-07-19 15:38:15}, priority = {2}, title = {One hundred years of positional information.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/8855666}, volume = {12}, year = {1996} }

TY - JOUR ID - citeulike:1467421 L3 - citeulike-article-id:1467421 N2 - One mechanism by which spatial patterns of cell differentiation could be specified during embryonic development and regeneration is based on positional information. Cells acquire a positional value with respect to boundaries and then interpret this in terms of a programme determined by their genetic constitution and developmental history. The signals and the molecular basis of such a system have both been rather well conserved. Recent work has shown that cells can respond to quite small differences in the concentrations of molecules whose concentration could provide positional information. IS - 9 JF - Trends Genet SN - 0168-9525 AD - Department of Anatomy and Developmental Biology, University College, London, UK. Lwolpert@ucl.ac.uk EP - 364 TI - One hundred years of positional information. VL - 12 SP - 359 KW - cells KW - signalling AU - Wolpert, L PY - 1996/09// UR - http://view.ncbi.nlm.nih.gov/pubmed/8855666 ER -