Active dendrites: colorful wings of the mysterious butterflies. Export

@article{citeulike:2859809, abstract = {Santiago Ram\'{o}n y Cajal had referred to neurons as the 'mysterious butterflies of the soul.' Wings of these butterflies - their dendrites - were traditionally considered as passive integrators of synaptic information. Owing to a growing body of experimental evidence, it is now widely accepted that these wings are colorful, endowed with a plethora of active conductances, with each family of these butterflies made of distinct hues and shades. Furthermore, rapidly evolving recent literature also provides direct and indirect demonstrations for activity-dependent plasticity of these active conductances, pointing toward chameleonic adaptability in these hues. These experimental findings firmly establish the immense computational power of a single neuron, and thus constitute a turning point toward the understanding of various aspects of neuronal information processing. In this brief historical perspective, we track important milestones in the chameleonic transmogrification of these mysterious butterflies.}, address = {Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA.}, author = {Johnston, Daniel and Narayanan, Rishikesh}, citeulike-article-id = {2859809}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tins.2008.03.004}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18471907}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18471907}, day = {7}, doi = {10.1016/j.tins.2008.03.004}, issn = {0166-2236}, journal = {Trends in neurosciences}, keywords = {bap, dendrites, integration, plasticity, review}, month = {May}, posted-at = {2008-06-03 20:26:28}, priority = {3}, title = {Active dendrites: colorful wings of the mysterious butterflies.}, url = {http://dx.doi.org/10.1016/j.tins.2008.03.004}, year = {2008} }

TY - JOUR ID - citeulike:2859809 L3 - citeulike-article-id:2859809 N2 - Santiago Ramón y Cajal had referred to neurons as the 'mysterious butterflies of the soul.' Wings of these butterflies - their dendrites - were traditionally considered as passive integrators of synaptic information. Owing to a growing body of experimental evidence, it is now widely accepted that these wings are colorful, endowed with a plethora of active conductances, with each family of these butterflies made of distinct hues and shades. Furthermore, rapidly evolving recent literature also provides direct and indirect demonstrations for activity-dependent plasticity of these active conductances, pointing toward chameleonic adaptability in these hues. These experimental findings firmly establish the immense computational power of a single neuron, and thus constitute a turning point toward the understanding of various aspects of neuronal information processing. In this brief historical perspective, we track important milestones in the chameleonic transmogrification of these mysterious butterflies. JF - Trends in neurosciences SN - 0166-2236 AD - Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA. TI - Active dendrites: colorful wings of the mysterious butterflies. KW - bap KW - dendrites KW - integration KW - plasticity KW - review AU - Johnston, Daniel AU - Narayanan, Rishikesh PY - 2008/05/07/ UR - http://dx.doi.org/10.1016/j.tins.2008.03.004 ER -