Physiological Sex Predicts Hybrid Sterility Regardless of Genotype Export

@article{citeulike:2201261, abstract = {Reproductive isolation between biological species is characterized by Haldane's rule, which states that the heterogametic sex (XY or ZW) suffers the most dysfunctional effects of hybridization. It has been hypothesized that, in addition to X-linked recessive genes, Haldane's rule also reflects the faster evolution of genes related to male reproduction (faster-male evolution). We used sex-reversed hybrid Xenopus to test faster-male evolution by examining the fertility of sex-reversed individuals with the genotype of the inverse phenotypic sex. Hybrid males are sterile and hybrid females are fertile irrespective of their genotypic sex. Gene expression profiles match these adult phenotypes, and our results demonstrate that faster-male evolution is the most likely mechanism producing hybrid male sterility. 10.1126/science.1148231}, author = {Malone, John H. and Michalak, P.}, citeulike-article-id = {2201261}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1148231}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/319/5859/59}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18174434}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18174434}, day = {4}, doi = {10.1126/science.1148231}, journal = {Science}, keywords = {hybridization, postzygotic, sex}, month = {January}, number = {5859}, pages = {59+}, posted-at = {2008-01-07 00:05:00}, priority = {2}, title = {Physiological Sex Predicts Hybrid Sterility Regardless of Genotype}, url = {http://dx.doi.org/10.1126/science.1148231}, volume = {319}, year = {2008} }

TY - JOUR ID - citeulike:2201261 L3 - citeulike-article-id:2201261 N2 - Reproductive isolation between biological species is characterized by Haldane's rule, which states that the heterogametic sex (XY or ZW) suffers the most dysfunctional effects of hybridization. It has been hypothesized that, in addition to X-linked recessive genes, Haldane's rule also reflects the faster evolution of genes related to male reproduction (faster-male evolution). We used sex-reversed hybrid Xenopus to test faster-male evolution by examining the fertility of sex-reversed individuals with the genotype of the inverse phenotypic sex. Hybrid males are sterile and hybrid females are fertile irrespective of their genotypic sex. Gene expression profiles match these adult phenotypes, and our results demonstrate that faster-male evolution is the most likely mechanism producing hybrid male sterility. 10.1126/science.1148231 IS - 5859 JF - Science TI - Physiological Sex Predicts Hybrid Sterility Regardless of Genotype VL - 319 SP - 59 KW - hybridization KW - postzygotic KW - sex AU - Malone, John AU - Michalak, P PY - 2008/01/04/ UR - http://dx.doi.org/10.1126/science.1148231 ER -