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Mathematical Biosciences, Vol. 42 (1 January 1978), pp. 257-266 Key: citeulike:4549435
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Using a rigorous mathematical analysis, the prediction of RNA secondary structure as a function of free energy is obtained. The iterative method effectively allows a search over the entire configuration space of the RNA molecule not possible by earlier methods. The approach also allows for the direct inclusion of the nearest neighbor or stacking energies.
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