The neural basis of puberty and adolescence Export

@article{citeulike:5686247, abstract = {The pubertal transition to adulthood involves both gonadal and behavioral maturation. A developmental clock, along with permissive signals that provide information on somatic growth, energy balance and season, time the awakening of gonadotropin releasing hormone (GnRH) neurons at the onset of puberty. High-frequency GnRH release results from disinhibition and activation of GnRH neurons at puberty onset, leading to gametogenesis and an increase in gonadal steroid hormone secretion. Steroid hormones, in turn, both remodel and activate neural circuits during adolescent brain development, leading to the development of sexual salience of sensory stimuli, sexual motivation, and expression of copulatory behaviors in specific social contexts. These influences of hormones on reproductive behavior depend in part on changes in the adolescent brain that occur independently of gonadal maturation. Reproductive maturity is therefore the product of developmentally timed, brain-driven and recurrent interactions between steroid hormones and the adolescent nervous system.}, author = {Sisk, Cheryl L. and Foster, Douglas L.}, citeulike-article-id = {5686247}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nn1326}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nn1326}, doi = {10.1038/nn1326}, journal = {Nat Neurosci}, keywords = {brain-development, hormones, lit-koerperbilder, nervous-system, neural-basis, neurology, puberty}, month = {October}, number = {10}, pages = {1040--1047}, posted-at = {2009-08-30 22:49:48}, priority = {2}, title = {The neural basis of puberty and adolescence}, url = {http://dx.doi.org/10.1038/nn1326}, volume = {7}, year = {2004} }

TY - JOUR ID - citeulike:5686247 L3 - citeulike-article-id:5686247 N2 - The pubertal transition to adulthood involves both gonadal and behavioral maturation. A developmental clock, along with permissive signals that provide information on somatic growth, energy balance and season, time the awakening of gonadotropin releasing hormone (GnRH) neurons at the onset of puberty. High-frequency GnRH release results from disinhibition and activation of GnRH neurons at puberty onset, leading to gametogenesis and an increase in gonadal steroid hormone secretion. Steroid hormones, in turn, both remodel and activate neural circuits during adolescent brain development, leading to the development of sexual salience of sensory stimuli, sexual motivation, and expression of copulatory behaviors in specific social contexts. These influences of hormones on reproductive behavior depend in part on changes in the adolescent brain that occur independently of gonadal maturation. Reproductive maturity is therefore the product of developmentally timed, brain-driven and recurrent interactions between steroid hormones and the adolescent nervous system. IS - 10 JF - Nat Neurosci EP - 1047 TI - The neural basis of puberty and adolescence VL - 7 SP - 1040 KW - brain-development KW - hormones KW - lit-koerperbilder KW - nervous-system KW - neural-basis KW - neurology KW - puberty AU - Sisk, Cheryl AU - Foster, Douglas PY - 2004/10// UR - http://dx.doi.org/10.1038/nn1326 ER -