Endoplasmic reticulum of animal cells and its organization into structural and functional domains. Export

@article{citeulike:3980691, abstract = {The endoplasmic reticulum (ER) in animal cells is an extensive, morphologically continuous network of membrane tubules and flattened cisternae. The ER is a multifunctional organelle; the synthesis of membrane lipids, membrane and secretory proteins, and the regulation of intracellular calcium are prominent among its array of functions. Many of these functions are not homogeneously distributed throughout the ER but rather are confined to distinct ER subregions or domains. This review describes the structural and functional organization of the ER and highlights the dynamic properties of the ER network and the mechanisms that support the positioning of ER membranes within the cell. Furthermore, we outline processes involved in the establishment and maintenance of an anisotropic distribution of ER-resident proteins and, thus, in the organization of the ER into functionally and morphologically different subregions.}, author = {Baumann, O. and Walz, B.}, citeulike-article-id = {3980691}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/11336391}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=11336391}, issn = {0074-7696}, journal = {International review of cytology}, keywords = {er}, pages = {149--214}, posted-at = {2009-01-30 09:53:38}, priority = {4}, title = {Endoplasmic reticulum of animal cells and its organization into structural and functional domains.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11336391}, volume = {205}, year = {2001} }

TY - JOUR ID - citeulike:3980691 L3 - citeulike-article-id:3980691 N2 - The endoplasmic reticulum (ER) in animal cells is an extensive, morphologically continuous network of membrane tubules and flattened cisternae. The ER is a multifunctional organelle; the synthesis of membrane lipids, membrane and secretory proteins, and the regulation of intracellular calcium are prominent among its array of functions. Many of these functions are not homogeneously distributed throughout the ER but rather are confined to distinct ER subregions or domains. This review describes the structural and functional organization of the ER and highlights the dynamic properties of the ER network and the mechanisms that support the positioning of ER membranes within the cell. Furthermore, we outline processes involved in the establishment and maintenance of an anisotropic distribution of ER-resident proteins and, thus, in the organization of the ER into functionally and morphologically different subregions. JF - International review of cytology SN - 0074-7696 EP - 214 TI - Endoplasmic reticulum of animal cells and its organization into structural and functional domains. VL - 205 SP - 149 KW - er AU - Baumann, O AU - Walz, B PY - 2001/// UR - http://view.ncbi.nlm.nih.gov/pubmed/11336391 ER -