A method for predicting hopper flow characteristics of pharmaceutical powders Export

@article{citeulike:4193345, abstract = {This communication correlates two empirical methods; flow in a rotating drum with flow in bench scale hoppers. The flow characteristics of 13 cohesive granular materials were studied in the gravitational displacement Rheometer (GDR) and compared to flow in hoppers of varying angle and discharge diameter at fixed temperature and moisture conditions. The GDR proved to be an effective and convenient tool for examining flow properties of pharmaceutical materials, both pure and mixtures. A flow Index obtained from GDR measurements is directly correlated to the flow through hoppers, providing a predictive method for hopper design and a convenient experimental test for screening materials and determining their suitability for specific hopper systems. Analysis of industrial scale hoppers will be addressed in future communication.}, author = {Faqih, A. and Alexander, A. and Muzzio, F. and Tomassone, M.}, citeulike-article-id = {4193345}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ces.2006.06.027}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0009250906007226}, doi = {10.1016/j.ces.2006.06.027}, issn = {00092509}, journal = {Chemical Engineering Science}, keywords = {granular\_flow, hopper, hopper\_flow, incline, particle\_technology, pharmaceutical}, month = {March}, number = {5}, pages = {1536--1542}, posted-at = {2009-03-18 21:48:50}, priority = {2}, title = {A method for predicting hopper flow characteristics of pharmaceutical powders}, url = {http://dx.doi.org/10.1016/j.ces.2006.06.027}, volume = {62}, year = {2007} }

TY - JOUR ID - citeulike:4193345 L3 - citeulike-article-id:4193345 N2 - This communication correlates two empirical methods; flow in a rotating drum with flow in bench scale hoppers. The flow characteristics of 13 cohesive granular materials were studied in the gravitational displacement Rheometer (GDR) and compared to flow in hoppers of varying angle and discharge diameter at fixed temperature and moisture conditions. The GDR proved to be an effective and convenient tool for examining flow properties of pharmaceutical materials, both pure and mixtures. A flow Index obtained from GDR measurements is directly correlated to the flow through hoppers, providing a predictive method for hopper design and a convenient experimental test for screening materials and determining their suitability for specific hopper systems. Analysis of industrial scale hoppers will be addressed in future communication. IS - 5 JF - Chemical Engineering Science SN - 00092509 EP - 1542 TI - A method for predicting hopper flow characteristics of pharmaceutical powders VL - 62 SP - 1536 KW - granular_flow KW - hopper KW - hopper_flow KW - incline KW - particle_technology KW - pharmaceutical AU - Faqih, A AU - Alexander, A AU - Muzzio, F AU - Tomassone, M PY - 2007/03// UR - http://dx.doi.org/10.1016/j.ces.2006.06.027 ER -