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Microrheology of Entangled F-Actin Solutions Export

Physical Review Letters, Vol. 91, No. 15. (Oct 2003), 158302.

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actin microrheology network weitz

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We measure the viscoelasticity of entangled F-actin over length scales between 1 and 100   μm using one- and two-particle microrheology; and directly identify two distinct microscopic contributions to the elasticity. Filament entanglements lead to a frequency-independent elastic modulus over an extended frequency range of 0.01–30   rad/ sec ⁡; this is probed with one-particle microrheology. Longitudinal fluctuations of the filaments increase the elastic modulus between 0.1 and 30   rad/ sec ⁡ at length scales up to the filament persistence length; this is probed by two-particle microrheology.


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