Mapping the Structural Core of Human Cerebral Cortex Export

@article{citeulike:2949792, abstract = {Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. By using diffusion spectrum imaging, we noninvasively mapped these pathways within and across cortical hemispheres in individual human participants. An analysis of the resulting large-scale structural brain networks reveals a structural core within posterior medial and parietal cerebral cortex, as well as several distinct temporal and frontal modules. Brain regions within the structural core share high degree, strength, and betweenness centrality, and they constitute connector hubs that link all major structural modules. The structural core contains brain regions that form the posterior components of the human default network. Looking both within and outside of core regions, we observed a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants. The spatial and topological centrality of the core within cortex suggests an important role in functional integration.}, author = {Hagmann, Patric and Cammoun, Leila and Gigandet, Xavier and Meuli, Reto and Honey, Christopher J. and Wedeen, Van J. and Sporns, Olaf}, citeulike-article-id = {2949792}, citeulike-linkout-0 = {http://dx.doi.org/10.1371/journal.pbio.0060159}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18597554}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18597554}, doi = {10.1371/journal.pbio.0060159}, issn = {1545-7885}, journal = {PLoS Biol}, month = {July}, number = {7}, pages = {e159+}, posted-at = {2009-04-06 17:23:14}, priority = {2}, publisher = {Public Library of Science}, title = {Mapping the Structural Core of Human Cerebral Cortex}, url = {http://dx.doi.org/10.1371/journal.pbio.0060159}, volume = {6}, year = {2008} }

TY - JOUR ID - citeulike:2949792 L3 - citeulike-article-id:2949792 N2 - Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. By using diffusion spectrum imaging, we noninvasively mapped these pathways within and across cortical hemispheres in individual human participants. An analysis of the resulting large-scale structural brain networks reveals a structural core within posterior medial and parietal cerebral cortex, as well as several distinct temporal and frontal modules. Brain regions within the structural core share high degree, strength, and betweenness centrality, and they constitute connector hubs that link all major structural modules. The structural core contains brain regions that form the posterior components of the human default network. Looking both within and outside of core regions, we observed a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants. The spatial and topological centrality of the core within cortex suggests an important role in functional integration. IS - 7 JF - PLoS Biol SN - 1545-7885 TI - Mapping the Structural Core of Human Cerebral Cortex PB - Public Library of Science VL - 6 SP - e159 AU - Hagmann, Patric AU - Cammoun, Leila AU - Gigandet, Xavier AU - Meuli, Reto AU - Honey, Christopher AU - Wedeen, Van AU - Sporns, Olaf PY - 2008/07/01/ UR - http://dx.doi.org/10.1371/journal.pbio.0060159 ER -