Sensitivity study for CT image use in Monte Carlo treatment planning Export

@article{Verhaegen2008, abstract = {An important step in Monte Carlo treatment planning (MCTP), which is commonly performed uncritically, is segmentation of the patient CT data into a voxel phantom for dose calculation. In addition to assigning mass densities to voxels, as is done in conventional TP, this entails assigning media. Mis-assignment of media can potentially lead to significant dose errors in MCTP. In this work, a test phantom with exact-known composition was used to study CT segmentation errors and to quantify subsequent MCTP inaccuracies. For our test cases, we observed dose errors in some regions of up to 10\% for 6 and 15 MV photons, more than 30\% for an 18 MeV electron beam and more than 40\% for 250 kVp photons. It is concluded that a careful CT calibration with a suitable phantom is essential. Generic calibrations and the use of commercial CT phantoms have to be critically assessed.}, author = {Verhaegen, Frank and Devic, Slobodan}, citeulike-article-id = {3758067}, citeulike-linkout-0 = {http://dx.doi.org/10.1088/0031-9155/50/5/016}, doi = {10.1088/0031-9155/50/5/016}, journal = {Physics in Medicine and Biology}, keywords = {calculation, ct, monte\_carlo, phantom, segmentation, voxel}, number = {5}, pages = {937--946}, posted-at = {2008-12-08 22:09:39}, priority = {2}, title = {Sensitivity study for CT image use in Monte Carlo treatment planning}, url = {http://dx.doi.org/10.1088/0031-9155/50/5/016}, volume = {50}, year = {2005} }

TY - JOUR ID - Verhaegen2008 L3 - citeulike-article-id:3758067 N2 - An important step in Monte Carlo treatment planning (MCTP), which is commonly performed uncritically, is segmentation of the patient CT data into a voxel phantom for dose calculation. In addition to assigning mass densities to voxels, as is done in conventional TP, this entails assigning media. Mis-assignment of media can potentially lead to significant dose errors in MCTP. In this work, a test phantom with exact-known composition was used to study CT segmentation errors and to quantify subsequent MCTP inaccuracies. For our test cases, we observed dose errors in some regions of up to 10% for 6 and 15 MV photons, more than 30% for an 18 MeV electron beam and more than 40% for 250 kVp photons. It is concluded that a careful CT calibration with a suitable phantom is essential. Generic calibrations and the use of commercial CT phantoms have to be critically assessed. IS - 5 JF - Physics in Medicine and Biology EP - 946 TI - Sensitivity study for CT image use in Monte Carlo treatment planning VL - 50 SP - 937 KW - calculation KW - ct KW - monte_carlo KW - phantom KW - segmentation KW - voxel AU - Verhaegen, Frank AU - Devic, Slobodan PY - 2005/// UR - http://dx.doi.org/10.1088/0031-9155/50/5/016 ER -