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SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data

by: Evguenia Kopylova, Laurent Noé, Hélène Touzet
Bioinformatics, Vol. 28, No. 24. (01 December 2012), pp. 3211-3217, doi:10.1093/bioinformatics/bts611  Key: citeulike:11474857

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Abstract

Motivation: The application of next-generation sequencing (NGS) technologies to RNAs directly extracted from a community of organisms yields a mixture of fragments characterizing both coding and non-coding types of RNAs. The task to distinguish among these and to further categorize the families of messenger RNAs and ribosomal RNAs (rRNAs) is an important step for examining gene expression patterns of an interactive environment and the phylogenetic classification of the constituting species.


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