Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. Export

@article{citeulike:3091051, abstract = {Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.}, address = {[1] INRA, UMR 1301, 400 route des Chappes, F-06903 Sophia-Antipolis, France. [2] CNRS, UMR 6243, 400 route des Chappes, F-06903 Sophia-Antipolis, France. [3] UNSA, UMR 1301, 400 route des Chappes, F-06903 Sophia-Antipolis, France.}, author = {Abad, Pierre and Gouzy, J\'{e}r\^{o}me and Aury, Jean-Marc M. and Castagnone-Sereno, Philippe and Danchin, Etienne G J G. and Deleury, Emeline and Perfus-Barbeoch, Laetitia and Anthouard, V\'{e}ronique and Artiguenave, Fran\c{c}ois and Blok, Vivian C C. and Caillaud, Marie-C\'{e}cile C. and Coutinho, Pedro M M. and Dasilva, Corinne and De Luca, Francesca and Deau, Florence and Esquibet, Magali and Flutre, Timoth\'{e} and Goldstone, Jared V V. and Hamamouch, Noureddine and Hewezi, Tarek and Jaillon, Olivier and Jubin, Claire and Leonetti, Paola and Magliano, Marc and Maier, Tom R R. and Markov, Gabriel V V. and McVeigh, Paul and Pesole, Graziano and Poulain, Julie and Robinson-Rechavi, Marc and Sallet, Erika and S\'{e}gurens, B\'{e}atrice and Steinbach, Delphine and Tytgat, Tom and Ugarte, Edgardo and van Ghelder, Cyril and Veronico, Pasqua and Baum, Thomas J J. and Blaxter, Mark and Bleve-Zacheo, Teresa and Davis, Eric L L. and Ewbank, Jonathan J J. and Favery, Bruno and Grenier, Eric and Henrissat, Bernard and Jones, John T T. and Laudet, Vincent and Maule, Aaron G G. and Quesneville, Hadi and Rosso, Marie-No\"{e}lle N. and Schiex, Thomas and Smant, Geert and Weissenbach, Jean and Wincker, Patrick}, citeulike-article-id = {3091051}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nbt.1482}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nbt.1482}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18660804}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18660804}, doi = {10.1038/nbt.1482}, issn = {1546-1696}, journal = {Nature biotechnology}, keywords = {genomesequencing, incognita, meloidogyne, model, nematode, parasite}, month = {July}, posted-at = {2008-09-26 23:37:00}, priority = {2}, title = {Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita.}, url = {http://dx.doi.org/10.1038/nbt.1482}, year = {2008} }

TY - JOUR ID - citeulike:3091051 L3 - citeulike-article-id:3091051 N2 - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies. JF - Nature biotechnology SN - 1546-1696 AD - [1] INRA, UMR 1301, 400 route des Chappes, F-06903 Sophia-Antipolis, France. [2] CNRS, UMR 6243, 400 route des Chappes, F-06903 Sophia-Antipolis, France. [3] UNSA, UMR 1301, 400 route des Chappes, F-06903 Sophia-Antipolis, France. TI - Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. KW - genomesequencing KW - incognita KW - meloidogyne KW - model KW - nematode KW - parasite AU - Abad, Pierre AU - Gouzy, Jérôme AU - Aury, Jean-Marc AU - Castagnone-Sereno, Philippe AU - Danchin, Etienne G J AU - Deleury, Emeline AU - Perfus-Barbeoch, Laetitia AU - Anthouard, Véronique AU - Artiguenave, François AU - Blok, Vivian C AU - Caillaud, Marie-Cécile AU - Coutinho, Pedro M AU - Dasilva, Corinne AU - De Luca, Francesca AU - Deau, Florence AU - Esquibet, Magali AU - Flutre, Timothé AU - Goldstone, Jared V AU - Hamamouch, Noureddine AU - Hewezi, Tarek AU - Jaillon, Olivier AU - Jubin, Claire AU - Leonetti, Paola AU - Magliano, Marc AU - Maier, Tom R AU - Markov, Gabriel V AU - McVeigh, Paul AU - Pesole, Graziano AU - Poulain, Julie AU - Robinson-Rechavi, Marc AU - Sallet, Erika AU - Ségurens, Béatrice AU - Steinbach, Delphine AU - Tytgat, Tom AU - Ugarte, Edgardo AU - van Ghelder, Cyril AU - Veronico, Pasqua AU - Baum, Thomas J AU - Blaxter, Mark AU - Bleve-Zacheo, Teresa AU - Davis, Eric L AU - Ewbank, Jonathan J AU - Favery, Bruno AU - Grenier, Eric AU - Henrissat, Bernard AU - Jones, John T AU - Laudet, Vincent AU - Maule, Aaron G AU - Quesneville, Hadi AU - Rosso, Marie-Noëlle AU - Schiex, Thomas AU - Smant, Geert AU - Weissenbach, Jean AU - Wincker, Patrick PY - 2008/07/27/ UR - http://dx.doi.org/10.1038/nbt.1482 ER -