A functional genetic variation of the 5-HT2a receptor affects human memory. Export

@article{citeulike:1479765, abstract = {Human memory capacity is highly variable across individuals and is influenced by both genetic and environmental factors. A roughly 50\% heritability estimate indicates that naturally occurring genetic variations have an important impact on this cognitive ability. Therefore, we investigated a functional variation of a memory-related serotonin receptor in 349 healthy young volunteers, and found 21\% poorer memory performance in subjects with the rare variant.}, address = {Division of Psychiatry Research, University of Z\"{u}rich, Lenggstr. 31, 8029 Z\"{u}rich, Switzerland. quervain@bli.unizh.ch}, author = {de Quervain, D. J. and Henke, K. and Aerni, A. and Coluccia, D. and Wollmer, M. A. and Hock, C. and Nitsch, R. M. and Papassotiropoulos, A.}, citeulike-article-id = {1479765}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nn1146}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/14566344}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=14566344}, doi = {10.1038/nn1146}, issn = {1097-6256}, journal = {Nat Neurosci}, keywords = {human, memory}, month = {November}, number = {11}, pages = {1141--1142}, posted-at = {2007-07-25 03:40:18}, priority = {2}, title = {A functional genetic variation of the 5-HT2a receptor affects human memory.}, url = {http://dx.doi.org/10.1038/nn1146}, volume = {6}, year = {2003} }

TY - JOUR ID - citeulike:1479765 L3 - citeulike-article-id:1479765 N2 - Human memory capacity is highly variable across individuals and is influenced by both genetic and environmental factors. A roughly 50% heritability estimate indicates that naturally occurring genetic variations have an important impact on this cognitive ability. Therefore, we investigated a functional variation of a memory-related serotonin receptor in 349 healthy young volunteers, and found 21% poorer memory performance in subjects with the rare variant. IS - 11 JF - Nat Neurosci SN - 1097-6256 AD - Division of Psychiatry Research, University of Zürich, Lenggstr. 31, 8029 Zürich, Switzerland. quervain@bli.unizh.ch EP - 1142 TI - A functional genetic variation of the 5-HT2a receptor affects human memory. VL - 6 SP - 1141 KW - human KW - memory AU - de Quervain, DJ AU - Henke, K AU - Aerni, A AU - Coluccia, D AU - Wollmer, MA AU - Hock, C AU - Nitsch, RM AU - Papassotiropoulos, A PY - 2003/11// UR - http://dx.doi.org/10.1038/nn1146 ER -