Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: quantitative analysis of Holter recordings Export

@article{citeulike:2113242, abstract = {OBJECTIVES. This study investigated the cycle length changes preceding the spontaneous onset of torsade de pointes in patients with acquired prolonged ventricular repolarization. BACKGROUND. Torsade de pointes is a polymorphic ventricular tachycardia generally associated with prolonged ventricular repolarization. Because torsade de pointes is not inducible by programmed electrical stimulation, quantitative analysis of Holter recordings of spontaneous episodes may clarify the mechanisms favoring the onset of torsade de pointes in actual clinical conditions. METHODS. The digitized Holter recordings of 12 patients were analyzed by a computerized Holter system (ATREC). All arrhythmias were grouped according to three classes: 1) isolated premature ventricular beats (n = 47,147, mean/patient [+/- SD] 3,929 +/- 11,571); 2) salvos of 2 to 4 consecutive beats (n = 2,003, mean/patient 167 +/- 359); 3) torsade de pointes > or = 5 beats (n = 105, mean/patient 9 +/- 11). For each patient and class of arrhythmias, six variables were computed from the 10 min and the 10 cycles preceding the event onset. RESULTS. A significant heart rate increase in the last minute (p}, author = {Locati, E. H. and Maison-Blanche, P. and Dejode, P. and Cauchemez, B. and Coumel, P.}, citeulike-article-id = {2113242}, citeulike-linkout-0 = {http://content.onlinejacc.org/cgi/content/abstract/25/7/1564}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/7539014}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=7539014}, day = {1}, journal = {J Am Coll Cardiol}, keywords = {holter, tdp}, month = {June}, number = {7}, pages = {1564--1575}, posted-at = {2007-12-14 11:38:14}, priority = {4}, title = {Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: quantitative analysis of Holter recordings}, url = {http://content.onlinejacc.org/cgi/content/abstract/25/7/1564}, volume = {25}, year = {1995} }

TY - JOUR ID - citeulike:2113242 L3 - citeulike-article-id:2113242 N2 - OBJECTIVES. This study investigated the cycle length changes preceding the spontaneous onset of torsade de pointes in patients with acquired prolonged ventricular repolarization. BACKGROUND. Torsade de pointes is a polymorphic ventricular tachycardia generally associated with prolonged ventricular repolarization. Because torsade de pointes is not inducible by programmed electrical stimulation, quantitative analysis of Holter recordings of spontaneous episodes may clarify the mechanisms favoring the onset of torsade de pointes in actual clinical conditions. METHODS. The digitized Holter recordings of 12 patients were analyzed by a computerized Holter system (ATREC). All arrhythmias were grouped according to three classes: 1) isolated premature ventricular beats (n = 47,147, mean/patient [+/- SD] 3,929 +/- 11,571); 2) salvos of 2 to 4 consecutive beats (n = 2,003, mean/patient 167 +/- 359); 3) torsade de pointes > or = 5 beats (n = 105, mean/patient 9 +/- 11). For each patient and class of arrhythmias, six variables were computed from the 10 min and the 10 cycles preceding the event onset. RESULTS. A significant heart rate increase in the last minute (p IS - 7 JF - J Am Coll Cardiol EP - 1575 TI - Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: quantitative analysis of Holter recordings VL - 25 SP - 1564 KW - holter KW - tdp AU - Locati, EH AU - Maison-Blanche, P AU - Dejode, P AU - Cauchemez, B AU - Coumel, P PY - 1995/06/01/ UR - http://content.onlinejacc.org/cgi/content/abstract/25/7/1564 ER -