The potential of phages to prevent MRSA infections. Export

@article{citeulike:3575843, abstract = {This short review attempts to examine whether there is a potential for the use of phages capable of infecting Staphylococcus aureus to eradicate or reduce nasal colonisation, thereby reducing the overall infection burden in patient populations identified as being at risk from MRSA infections. There is clear evidence that nasal decolonisation may be of benefit to certain patient groups and also that phages can effectively combat experimentally induced S. aureus infections in animals. However, this is not in itself enough to validate the use of phages for decolonisation and, given the appearance of strains resistant to currently used topical antibiotics, there is a need for clinical trials of this prophylactic use of phages.}, author = {Mann, N. H.}, citeulike-article-id = {3575843}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.resmic.2008.04.003}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0923250808000570}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18541414}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18541414}, doi = {10.1016/j.resmic.2008.04.003}, issn = {0923-2508}, journal = {Research in microbiology}, keywords = {aureus, mrsa, staphylococcus}, month = {June}, number = {5}, pages = {400--405}, posted-at = {2008-12-17 12:32:56}, priority = {2}, title = {The potential of phages to prevent MRSA infections.}, url = {http://dx.doi.org/10.1016/j.resmic.2008.04.003}, volume = {159}, year = {2008} }

TY - JOUR ID - citeulike:3575843 L3 - citeulike-article-id:3575843 N2 - This short review attempts to examine whether there is a potential for the use of phages capable of infecting Staphylococcus aureus to eradicate or reduce nasal colonisation, thereby reducing the overall infection burden in patient populations identified as being at risk from MRSA infections. There is clear evidence that nasal decolonisation may be of benefit to certain patient groups and also that phages can effectively combat experimentally induced S. aureus infections in animals. However, this is not in itself enough to validate the use of phages for decolonisation and, given the appearance of strains resistant to currently used topical antibiotics, there is a need for clinical trials of this prophylactic use of phages. IS - 5 JF - Research in microbiology SN - 0923-2508 EP - 405 TI - The potential of phages to prevent MRSA infections. VL - 159 SP - 400 KW - aureus KW - mrsa KW - staphylococcus AU - Mann, NH PY - 2008/06// UR - http://dx.doi.org/10.1016/j.resmic.2008.04.003 ER -