Multi-agent modeling of the immune system: The situated cellular agents approach Export

@article{citeulike:4802134, abstract = {The Immune System (IS) is the main defense mechanism of higher level organisms to antigens (microscopic threats, such as viruses and bacteria). It is a very complex system, genuinely distributed and providing mechanisms of adaptation to unknown threats. The most relevant characteristics of the IS, such as learning capabilities and the possibility to tackle unknown threats in any part of the body, are a consequence of interactions among its composing parts. This paper describes a Multi-Agent Systems modeling approach to the study of interactions in the IS, adopting the Situated Cellular Agents (SCA) model. After a brief description of the IS, an overview of current modeling and simulation approaches will be given. The SCA model will be then introduced and exploited in order to model some relevant elements and mechanisms of the IS. This work is one of the results of an interdisciplinary research that has involved immunologists of the Advanced Biotechnology Center of Genova and computer scientists of the University of Milan-Bicocca.}, address = {Amsterdam, The Netherlands, The Netherlands}, author = {Bandini, Stefania and Manzoni, Sara and Vizzari, Giuseppe}, citeulike-article-id = {4802134}, citeulike-linkout-0 = {http://portal.acm.org/citation.cfm?id=1375361}, issn = {1574-1702}, journal = {Multiagent Grid Syst.}, keywords = {agents, cell, immune, modelling}, number = {2}, pages = {173--182}, posted-at = {2009-06-16 12:05:07}, priority = {2}, publisher = {IOS Press}, title = {Multi-agent modeling of the immune system: The situated cellular agents approach}, url = {http://portal.acm.org/citation.cfm?id=1375361}, volume = {3}, year = {2007} }

TY - JOUR ID - citeulike:4802134 L3 - citeulike-article-id:4802134 N2 - The Immune System (IS) is the main defense mechanism of higher level organisms to antigens (microscopic threats, such as viruses and bacteria). It is a very complex system, genuinely distributed and providing mechanisms of adaptation to unknown threats. The most relevant characteristics of the IS, such as learning capabilities and the possibility to tackle unknown threats in any part of the body, are a consequence of interactions among its composing parts. This paper describes a Multi-Agent Systems modeling approach to the study of interactions in the IS, adopting the Situated Cellular Agents (SCA) model. After a brief description of the IS, an overview of current modeling and simulation approaches will be given. The SCA model will be then introduced and exploited in order to model some relevant elements and mechanisms of the IS. This work is one of the results of an interdisciplinary research that has involved immunologists of the Advanced Biotechnology Center of Genova and computer scientists of the University of Milan-Bicocca. IS - 2 JF - Multiagent Grid Syst. SN - 1574-1702 AD - Amsterdam, The Netherlands, The Netherlands EP - 182 TI - Multi-agent modeling of the immune system: The situated cellular agents approach PB - IOS Press VL - 3 SP - 173 KW - agents KW - cell KW - immune KW - modelling AU - Bandini, Stefania AU - Manzoni, Sara AU - Vizzari, Giuseppe PY - 2007/// UR - http://portal.acm.org/citation.cfm?id=1375361 ER -