Host-Bacterial Mutualism in the Human Intestine Export

@article{citeulike:582292, abstract = {The distal human intestine represents an anaerobic bioreactor programmed with an enormous population of bacteria, dominated by relatively few divisions that are highly diverse at the strain/subspecies level. This microbiota and its collective genomes (microbiome) provide us with genetic and metabolic attributes we have not been required to evolve on our own, including the ability to harvest otherwise inaccessible nutrients. New studies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements our biology in ways that are mutually beneficial. We are also starting to understand how certain keystone members of the microbiota operate to maintain the stability and functional adaptability of this microbial organ. 10.1126/science.1104816}, address = {Center for Genome Sciences, Washington University School of Medicine, St. Louis, MO 63108, USA.}, author = {Backhed, Fredrik and Ley, Ruth E. and Sonnenburg, Justin L. and Peterson, Daniel A. and Gordon, Jeffrey I.}, citeulike-article-id = {582292}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1104816}, citeulike-linkout-1 = {http://www.sciencemag.org/content/307/5717/1915.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/307/5717/1915.full.pdf}, citeulike-linkout-3 = {http://www.sciencemag.org/cgi/content/abstract/307/5717/1915}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/15790844}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=15790844}, day = {25}, doi = {10.1126/science.1104816}, issn = {1095-9203}, journal = {Science}, keywords = {commensal, ecology, gut, microbial, mutualism}, month = {March}, number = {5717}, pages = {1915--1920}, posted-at = {2009-10-21 14:17:24}, priority = {2}, title = {Host-Bacterial Mutualism in the Human Intestine}, url = {http://dx.doi.org/10.1126/science.1104816}, volume = {307}, year = {2005} }

TY - JOUR ID - citeulike:582292 L3 - citeulike-article-id:582292 N2 - The distal human intestine represents an anaerobic bioreactor programmed with an enormous population of bacteria, dominated by relatively few divisions that are highly diverse at the strain/subspecies level. This microbiota and its collective genomes (microbiome) provide us with genetic and metabolic attributes we have not been required to evolve on our own, including the ability to harvest otherwise inaccessible nutrients. New studies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements our biology in ways that are mutually beneficial. We are also starting to understand how certain keystone members of the microbiota operate to maintain the stability and functional adaptability of this microbial organ. 10.1126/science.1104816 IS - 5717 JF - Science SN - 1095-9203 AD - Center for Genome Sciences, Washington University School of Medicine, St. Louis, MO 63108, USA. EP - 1920 TI - Host-Bacterial Mutualism in the Human Intestine VL - 307 SP - 1915 KW - commensal KW - ecology KW - gut KW - microbial KW - mutualism AU - Backhed, Fredrik AU - Ley, Ruth AU - Sonnenburg, Justin AU - Peterson, Daniel AU - Gordon, Jeffrey PY - 2005/03/25/ UR - http://dx.doi.org/10.1126/science.1104816 ER -