Collective Cell Migration Export

@article{citeulike:6061285, abstract = {For all animals, cell migration is an essential and highly regulated process. Cells migrate to shape tissues, to vascularize tissues, in wound healing, and as part of the immune response. Unfortunately, tumor cells can also become migratory and invade surrounding tissues. Some cells migrate as individuals, but many cell types will, under physiological conditions, migrate collectively in tightly or loosely associated groups. This includes invasive tumor cells. This review discusses different types of collective cell migration, including sheet movement, sprouting and branching, streams, and free groups, and highlights recent findings that provide insight into cells' organization and behavior. Cells performing collective migration share many cell biological characteristics with independently migrating cells but, by affecting one another mechanically and via signaling, these cell groups are subject to additional regulation and constraints. New properties that emerge from this connectivity can contribute to shaping, guiding, and ultimately ensuring tissue function.}, author = {R{\o}rth, Pernille}, citeulike-article-id = {6061285}, citeulike-linkout-0 = {http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.cellbio.042308.113231}, citeulike-linkout-1 = {http://dx.doi.org/10.1146/annurev.cellbio.042308.113231}, doi = {10.1146/annurev.cellbio.042308.113231}, journal = {Annual Review of Cell and Developmental Biology}, keywords = {cell\_migration, review, stem, stem\_cell}, number = {1}, pages = {407--429}, posted-at = {2009-11-03 18:35:03}, priority = {2}, title = {Collective Cell Migration}, url = {http://dx.doi.org/10.1146/annurev.cellbio.042308.113231}, volume = {25}, year = {2009} }

TY - JOUR ID - citeulike:6061285 L3 - citeulike-article-id:6061285 N2 - For all animals, cell migration is an essential and highly regulated process. Cells migrate to shape tissues, to vascularize tissues, in wound healing, and as part of the immune response. Unfortunately, tumor cells can also become migratory and invade surrounding tissues. Some cells migrate as individuals, but many cell types will, under physiological conditions, migrate collectively in tightly or loosely associated groups. This includes invasive tumor cells. This review discusses different types of collective cell migration, including sheet movement, sprouting and branching, streams, and free groups, and highlights recent findings that provide insight into cells' organization and behavior. Cells performing collective migration share many cell biological characteristics with independently migrating cells but, by affecting one another mechanically and via signaling, these cell groups are subject to additional regulation and constraints. New properties that emerge from this connectivity can contribute to shaping, guiding, and ultimately ensuring tissue function. IS - 1 JF - Annual Review of Cell and Developmental Biology EP - 429 TI - Collective Cell Migration VL - 25 SP - 407 KW - cell_migration KW - review KW - stem KW - stem_cell AU - Rørth, Pernille PY - 2009/// UR - http://dx.doi.org/10.1146/annurev.cellbio.042308.113231 ER -