A Red Cy3-Based Biarsenical Fluorescent Probe Targeted to a Complementary Binding Peptide

@article{citeulike:1408190, abstract = {Abstract: We have synthesized a red biarsenical fluorescent probe, AsCy3, with good photostability, low pH sensitivity, high absorbance, and good quantum yield. It is directed specifically to a small tetracysteine peptide binding motif, Cy3TAG (CysCysLysAlaGluAlaAlaCysCys), in the presence of other tetracysteine tags. This new probe provides a FRET partner to biarsenical dye FlAsH, making this discovery an important step toward a whole toolkit of colored probes directed to different small peptide motifs.}, address = {Cell Biology and Biochemistry Group, Pacific Northwest National Laboratory, Richland, Washington 99352}, author = {Cao, H. and Xiong, Y. and Wang, T. and Chen, B. and Squier, T. C. and Mayer, M. U.}, citeulike-article-id = {1408190}, doi = {10.1021/ja070003c}, journal = {J. Am. Chem. Soc.}, keywords = {bioconjugation, flash, fluorescence, reash}, month = {June}, posted-at = {2008-10-15 16:24:18}, priority = {2}, title = {A Red Cy3-Based Biarsenical Fluorescent Probe Targeted to a Complementary Binding Peptide}, url = {http://dx.doi.org/10.1021/ja070003c}, year = {2007} }

TY - JOUR ID - citeulike:1408190 L3 - citeulike-article-id:1408190 N2 - Abstract: We have synthesized a red biarsenical fluorescent probe, AsCy3, with good photostability, low pH sensitivity, high absorbance, and good quantum yield. It is directed specifically to a small tetracysteine peptide binding motif, Cy3TAG (CysCysLysAlaGluAlaAlaCysCys), in the presence of other tetracysteine tags. This new probe provides a FRET partner to biarsenical dye FlAsH, making this discovery an important step toward a whole toolkit of colored probes directed to different small peptide motifs. JF - J. Am. Chem. Soc. AD - Cell Biology and Biochemistry Group, Pacific Northwest National Laboratory, Richland, Washington 99352 TI - A Red Cy3-Based Biarsenical Fluorescent Probe Targeted to a Complementary Binding Peptide KW - bioconjugation KW - flash KW - fluorescence KW - reash AU - Cao, H AU - Xiong, Y AU - Wang, T AU - Chen, B AU - Squier, TC AU - Mayer, MU PY - 2007/06/22/ UR - http://dx.doi.org/10.1021/ja070003c ER -