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A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell Export

J. Am. Chem. Soc. (12 November 2008)

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cadmium_binding cd fluorescence

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Abstract: A highly selective and sensitive OFF-ON fluorescent sensor 1, employing the PET mechanism, was designed and synthesized. It could be used to detect Cd2+ ion in aqueous solution and to image Cd2+ ion in living cells. The fluorescence intensity significantly enhanced about 195-fold and the quantum yield increased almost 100-fold. Moreover the fluorescence intensity of 1 increased linearly with high sensitivity (01 ¼M) toward Cd2+.


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