Protein folding and quality control in the endoplasmic reticulum Export

@article{citeulike:4509788, abstract = {The endoplasmic reticulum (ER) is a highly versatile protein factory that is equipped with chaperones and folding enzymes essential for protein folding. ER quality control guided by these chaperones is essential for life. Whereas correctly folded proteins are exported from the ER, misfolded proteins are retained and selectively degraded. At least two main chaperone classes, BiP and calnexin/calreticulin, are active in ER quality control. Folding factors usually are found in complexes. Recent work emphasises more than ever that chaperones act in concert with co-factors and with each other.}, author = {Kleizen, B.}, citeulike-article-id = {4509788}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ceb.2004.06.012}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0955-0674(04)00081-X}, doi = {10.1016/j.ceb.2004.06.012}, issn = {09550674}, journal = {Current Opinion in Cell Biology}, keywords = {calnexin, er}, month = {August}, number = {4}, pages = {343--349}, posted-at = {2009-05-13 11:54:34}, priority = {2}, title = {Protein folding and quality control in the endoplasmic reticulum}, url = {http://dx.doi.org/10.1016/j.ceb.2004.06.012}, volume = {16}, year = {2004} }

TY - JOUR ID - citeulike:4509788 L3 - citeulike-article-id:4509788 N2 - The endoplasmic reticulum (ER) is a highly versatile protein factory that is equipped with chaperones and folding enzymes essential for protein folding. ER quality control guided by these chaperones is essential for life. Whereas correctly folded proteins are exported from the ER, misfolded proteins are retained and selectively degraded. At least two main chaperone classes, BiP and calnexin/calreticulin, are active in ER quality control. Folding factors usually are found in complexes. Recent work emphasises more than ever that chaperones act in concert with co-factors and with each other. IS - 4 JF - Current Opinion in Cell Biology SN - 09550674 EP - 349 TI - Protein folding and quality control in the endoplasmic reticulum VL - 16 SP - 343 KW - calnexin KW - er AU - Kleizen, B PY - 2004/08// UR - http://dx.doi.org/10.1016/j.ceb.2004.06.012 ER -