Coincidence detection in phosphoinositide signaling Export

@article{citeulike:590662, abstract = {Phosphoinositide lipids function as both signaling molecules and as compartment-specific localization signals for phosphoinositide-binding proteins. In recent years, both phosphoinositides and phosphoinositide-binding proteins have been reported to display a restricted, rather than a uniform, distribution across intracellular membranes. Here, we examine recent data documenting the restricted distribution of both phosphoinositides and phosphoinositide-binding proteins and examine how phosphoinositide-binding proteins might engage multiple binding partners to achieve these restricted localizations, effectively acting as detectors of coincident localization signals.}, address = {Department of Biochemistry, School of Medical Sciences, University of Bristol, UK.}, author = {Carlton, Jez G. and Cullen, Peter J.}, citeulike-article-id = {590662}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tcb.2005.08.005}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0962892405002059}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/16139503}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=16139503}, doi = {10.1016/j.tcb.2005.08.005}, issn = {09628924}, journal = {Trends in Cell Biology}, keywords = {phosphoinositide, snx}, month = {October}, number = {10}, pages = {540--547}, posted-at = {2009-10-27 11:26:55}, priority = {2}, title = {Coincidence detection in phosphoinositide signaling}, url = {http://dx.doi.org/10.1016/j.tcb.2005.08.005}, volume = {15}, year = {2005} }

TY - JOUR ID - citeulike:590662 L3 - citeulike-article-id:590662 N2 - Phosphoinositide lipids function as both signaling molecules and as compartment-specific localization signals for phosphoinositide-binding proteins. In recent years, both phosphoinositides and phosphoinositide-binding proteins have been reported to display a restricted, rather than a uniform, distribution across intracellular membranes. Here, we examine recent data documenting the restricted distribution of both phosphoinositides and phosphoinositide-binding proteins and examine how phosphoinositide-binding proteins might engage multiple binding partners to achieve these restricted localizations, effectively acting as detectors of coincident localization signals. IS - 10 JF - Trends in Cell Biology SN - 09628924 AD - Department of Biochemistry, School of Medical Sciences, University of Bristol, UK. EP - 547 TI - Coincidence detection in phosphoinositide signaling VL - 15 SP - 540 KW - phosphoinositide KW - snx AU - Carlton, Jez AU - Cullen, Peter PY - 2005/10// UR - http://dx.doi.org/10.1016/j.tcb.2005.08.005 ER -