Caveats of caveolin-1 in cancer progression. Export

@article{citeulike:3154897, abstract = {Caveolin-1, an essential scaffold protein of caveolae and cellular transport processes, lately gained recognition as a stage- and tissue-specific tumor modulator in vivo. Patient studies and rodent models corroborated its janus-faced role as a tumor suppressor in non-neoplastic tissue, its down-regulation (loss of function) upon transformation and its re-expression (regain of function) in advanced-stage metastatic and multidrug resistant tumors. This review is focussed on the role of caveolin-1 in metastasis and angiogenesis and its clinical implications as a prognostic marker in cancer progression.}, address = {Department of Medicine II, Klinikum rechts der Isar, Technical University of M\"{u}nchen, Ismaningerstrasse 22, D-81675 M\"{u}nchen, Germany.}, author = {Burgermeister, E. and Liscovitch, M. and R\"{o}cken, C. and Schmid, R. M. and Ebert, M. P.}, citeulike-article-id = {3154897}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.canlet.2008.03.055}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18482795}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18482795}, doi = {10.1016/j.canlet.2008.03.055}, issn = {0304-3835}, journal = {Cancer letters}, keywords = {angiogenesis, cancer, caveolin-1, review}, month = {September}, number = {2}, pages = {187--201}, posted-at = {2008-08-26 10:20:57}, priority = {2}, title = {Caveats of caveolin-1 in cancer progression.}, url = {http://dx.doi.org/10.1016/j.canlet.2008.03.055}, volume = {268}, year = {2008} }

TY - JOUR ID - citeulike:3154897 L3 - citeulike-article-id:3154897 N2 - Caveolin-1, an essential scaffold protein of caveolae and cellular transport processes, lately gained recognition as a stage- and tissue-specific tumor modulator in vivo. Patient studies and rodent models corroborated its janus-faced role as a tumor suppressor in non-neoplastic tissue, its down-regulation (loss of function) upon transformation and its re-expression (regain of function) in advanced-stage metastatic and multidrug resistant tumors. This review is focussed on the role of caveolin-1 in metastasis and angiogenesis and its clinical implications as a prognostic marker in cancer progression. IS - 2 JF - Cancer letters SN - 0304-3835 AD - Department of Medicine II, Klinikum rechts der Isar, Technical University of München, Ismaningerstrasse 22, D-81675 München, Germany. EP - 201 TI - Caveats of caveolin-1 in cancer progression. VL - 268 SP - 187 KW - angiogenesis KW - cancer KW - caveolin-1 KW - review AU - Burgermeister, E AU - Liscovitch, M AU - Röcken, C AU - Schmid, RM AU - Ebert, MP PY - 2008/09/18/ UR - http://dx.doi.org/10.1016/j.canlet.2008.03.055 ER -