Potassium. Export

@article{citeulike:247844, abstract = {In a logical, stepwise approach to patients presenting with hypokalaemia or hyperkalaemia the clinician must first recognise circumstances in which the dyskalaemia represents a clinical emergency because therapy then takes precedence over diagnosis. If a dyskalaemia has been present for a long time, there is an abnormal renal handling of K+. The next step to analyse is the rate of excretion of K+ and, if necessary, its two components (urine flow rate and K+ concentration in the cortical collecting duct [CCD]) analysed independently. If the K+ concentration in the CCD is not in the expected range, its basis should be defined at the ion-channel level in the CCD from clinical information that can be used to deduce the relative rates of reabsorption of Na+ and Cl- in the CCD. This analysis provides the basis for diagnosis and may indicate where non-emergency therapy should then be directed.}, address = {Division of Nephrology, St Michael's Hospital, University of Toronto, Ontario, Canada. mitchell.halperin@utoronto.ca}, author = {Halperin, M. L. and Kamel, K. S.}, citeulike-article-id = {247844}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/9672294}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=9672294}, day = {11}, issn = {0140-6736}, journal = {Lancet}, keywords = {k, potassium}, month = {July}, number = {9122}, pages = {135--140}, posted-at = {2005-07-06 15:49:41}, priority = {0}, title = {Potassium.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/9672294}, volume = {352}, year = {1998} }

TY - JOUR ID - citeulike:247844 L3 - citeulike-article-id:247844 N2 - In a logical, stepwise approach to patients presenting with hypokalaemia or hyperkalaemia the clinician must first recognise circumstances in which the dyskalaemia represents a clinical emergency because therapy then takes precedence over diagnosis. If a dyskalaemia has been present for a long time, there is an abnormal renal handling of K+. The next step to analyse is the rate of excretion of K+ and, if necessary, its two components (urine flow rate and K+ concentration in the cortical collecting duct [CCD]) analysed independently. If the K+ concentration in the CCD is not in the expected range, its basis should be defined at the ion-channel level in the CCD from clinical information that can be used to deduce the relative rates of reabsorption of Na+ and Cl- in the CCD. This analysis provides the basis for diagnosis and may indicate where non-emergency therapy should then be directed. IS - 9122 JF - Lancet SN - 0140-6736 AD - Division of Nephrology, St Michael's Hospital, University of Toronto, Ontario, Canada. mitchell.halperin@utoronto.ca EP - 140 TI - Potassium. VL - 352 SP - 135 KW - k KW - potassium AU - Halperin, ML AU - Kamel, KS PY - 1998/07/11/ UR - http://view.ncbi.nlm.nih.gov/pubmed/9672294 ER -