Simultaneous determination of adenine guanine and thymine at multi-walled carbon nanotubes incorporated with poly(new fuchsin) composite film Export

@article{citeulike:4179597, abstract = {A composite film (MWCNTs–PNF) which contains multi-walled carbon nanotubes (MWCNTs) along with the incorporation of poly(new fuchsin) (PNF) has been synthesized on glassy carbon electrode (GCE), gold (Au) and indium tin oxide (ITO) by potentiostatic methods. The presence of MWCNTs in the composite film enhances surface coverage concentration ( Γ ) of PNF to ≈176.5\%, and increases the electron transfer rate constant ( k s ) to ≈346\%. The composite film also exhibits promising enhanced electrocatalytic activity towards the mixture of biochemical compounds such as adenine (AD), guanine (GU) and thymine (THY). The surface morphology of the composite film deposited on ITO has been studied using scanning electron microscopy and atomic force microscopy. These two techniques reveal that the PNF incorporated on MWCNTs. Electrochemical quartz crystal microbalance study reveals the enhancement in the functional properties of MWCNTs and PNF. The electrocatalytic responses of analytes at MWCNTs and MWCNTs–PNF films were measured using both cyclic voltammetry (CV) and differential pulse voltammetry (DPV). From electrocatalysis studies, well separated voltammetric peaks have been obtained at the composite film for AD, GU and THY, with the peak separation of 320.3 and 132.7 mV between GU–AD and AD–THY respectively. The sensitivity of the composite film towards AD, GU and THY in DPV technique is 218.18, 12.62 and 78.22 mA M −1  cm −2 respectively, which are higher than MWCNTs film. Further, electroanalytical studies of AD, GU and THY present in single-strand deoxyribonucleic acid (ssDNA) have been carried out using semi-derivative CV and DPV.}, author = {Tang, Ching and Umasankar, Yogeswaran and Chen, Shen-Ming}, citeulike-article-id = {4179597}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.aca.2009.01.055}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0003267009001846}, day = {16}, doi = {10.1016/j.aca.2009.01.055}, issn = {00032670}, journal = {Analytica Chimica Acta}, keywords = {acid, adenine, carbon, composite, deoxyribonucleic, dna, electrocatalysis, electrodes, film, guanine, modified, multiwall, nanotubes, thymine}, month = {March}, number = {1}, pages = {19--27}, posted-at = {2009-03-15 18:23:28}, priority = {2}, title = {Simultaneous determination of adenine guanine and thymine at multi-walled carbon nanotubes incorporated with poly(new fuchsin) composite film}, url = {http://dx.doi.org/10.1016/j.aca.2009.01.055}, volume = {636}, year = {2009} }

TY - JOUR ID - citeulike:4179597 L3 - citeulike-article-id:4179597 N2 - A composite film (MWCNTs–PNF) which contains multi-walled carbon nanotubes (MWCNTs) along with the incorporation of poly(new fuchsin) (PNF) has been synthesized on glassy carbon electrode (GCE), gold (Au) and indium tin oxide (ITO) by potentiostatic methods. The presence of MWCNTs in the composite film enhances surface coverage concentration ( Γ ) of PNF to ≈176.5%, and increases the electron transfer rate constant ( k s ) to ≈346%. The composite film also exhibits promising enhanced electrocatalytic activity towards the mixture of biochemical compounds such as adenine (AD), guanine (GU) and thymine (THY). The surface morphology of the composite film deposited on ITO has been studied using scanning electron microscopy and atomic force microscopy. These two techniques reveal that the PNF incorporated on MWCNTs. Electrochemical quartz crystal microbalance study reveals the enhancement in the functional properties of MWCNTs and PNF. The electrocatalytic responses of analytes at MWCNTs and MWCNTs–PNF films were measured using both cyclic voltammetry (CV) and differential pulse voltammetry (DPV). From electrocatalysis studies, well separated voltammetric peaks have been obtained at the composite film for AD, GU and THY, with the peak separation of 320.3 and 132.7 mV between GU–AD and AD–THY respectively. The sensitivity of the composite film towards AD, GU and THY in DPV technique is 218.18, 12.62 and 78.22 mA M −1  cm −2 respectively, which are higher than MWCNTs film. Further, electroanalytical studies of AD, GU and THY present in single-strand deoxyribonucleic acid (ssDNA) have been carried out using semi-derivative CV and DPV. IS - 1 JF - Analytica Chimica Acta SN - 00032670 EP - 27 TI - Simultaneous determination of adenine guanine and thymine at multi-walled carbon nanotubes incorporated with poly(new fuchsin) composite film VL - 636 SP - 19 KW - acid KW - adenine KW - carbon KW - composite KW - deoxyribonucleic KW - dna KW - electrocatalysis KW - electrodes KW - film KW - guanine KW - modified KW - multiwall KW - nanotubes KW - thymine AU - Tang, Ching AU - Umasankar, Yogeswaran AU - Chen, Shen-Ming PY - 2009/03/16/ UR - http://dx.doi.org/10.1016/j.aca.2009.01.055 ER -