Environmental exposures, toxicologic mechanisms, and adverse pregnancy outcomes. Export

@article{citeulike:3989874, abstract = {Environmental risk factors (defined as those agents and stresses that are generally the responsibility of environmental agencies) are often tangible indicators of economic and social disparity in the United States. Many site-specific analyses have reported that communities of color and poverty are exposed more often and more intensively to such environmental hazards as lead, air pollution, agrochemicals, incinerator emissions, and releases from hazardous waste sites. Thus, exposures to these toxicants may explain part of the socioeconomic disparity that is observed in terms of risks of adverse pregnancy outcomes. The purpose of this study was to describe the associations between certain environmental exposures and reproductive outcomes through a discussion of both epidemiologic and animal model studies. In addition, we list potential sources of exposure data and describe physiologic changes in pregnancy that may increase the likelihood of both external exposures and increased internal dose. Several models for further study of environmental risk factors are suggested to increase our understanding of gene-environment interactions toward the goal of indentifying preventable risk factors to improve reproductive outcomes of particular concern to disadvantaged populations.}, author = {Silbergeld, E. K. and Patrick, T. E.}, citeulike-article-id = {3989874}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ajog.2004.06.117}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15891707}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15891707}, doi = {10.1016/j.ajog.2004.06.117}, issn = {0002-9378}, journal = {American journal of obstetrics and gynecology}, keywords = {adverse\_reproductive\_outcomes, environmental\_exposure, pollution, toxicology}, month = {May}, number = {5 Suppl}, posted-at = {2009-02-01 03:57:10}, priority = {2}, title = {Environmental exposures, toxicologic mechanisms, and adverse pregnancy outcomes.}, url = {http://dx.doi.org/10.1016/j.ajog.2004.06.117}, volume = {192}, year = {2005} }

TY - JOUR ID - citeulike:3989874 L3 - citeulike-article-id:3989874 N2 - Environmental risk factors (defined as those agents and stresses that are generally the responsibility of environmental agencies) are often tangible indicators of economic and social disparity in the United States. Many site-specific analyses have reported that communities of color and poverty are exposed more often and more intensively to such environmental hazards as lead, air pollution, agrochemicals, incinerator emissions, and releases from hazardous waste sites. Thus, exposures to these toxicants may explain part of the socioeconomic disparity that is observed in terms of risks of adverse pregnancy outcomes. The purpose of this study was to describe the associations between certain environmental exposures and reproductive outcomes through a discussion of both epidemiologic and animal model studies. In addition, we list potential sources of exposure data and describe physiologic changes in pregnancy that may increase the likelihood of both external exposures and increased internal dose. Several models for further study of environmental risk factors are suggested to increase our understanding of gene-environment interactions toward the goal of indentifying preventable risk factors to improve reproductive outcomes of particular concern to disadvantaged populations. IS - 5 Suppl JF - American journal of obstetrics and gynecology SN - 0002-9378 TI - Environmental exposures, toxicologic mechanisms, and adverse pregnancy outcomes. VL - 192 KW - adverse_reproductive_outcomes KW - environmental_exposure KW - pollution KW - toxicology AU - Silbergeld, EK AU - Patrick, TE PY - 2005/05// UR - http://dx.doi.org/10.1016/j.ajog.2004.06.117 ER -