Oxygen mass transfer in a model three-dimensional artery. Export

@article{coppola2008, abstract = {Arterial geometry is commonly non-planar and associated with swirling blood flow. In this study, we examine the effect of arterial three-dimensionality on the distribution of wall shear stress (WSS) and the mass transfer of oxygen from the blood to the vessel wall in a U-bend, by modelling the blood vessels as either cylindrical or helical conduits. The results show that under physiological flow conditions, three-dimensionality can reduce both the range and extent of low WSS regions and substantially increase oxygen flux through the walls. The Sherwood number and WSS distributions between the three-dimensional helical model and a human coronary artery show remarkable qualitative agreement, implying that coronary arteries may potentially be described with a relatively simple idealized three-dimensional model, characterized by a small number of well-defined geometric parameters. The flow pattern downstream of a planar bend results in separation of the Sh number and WSS effects, a finding that implies means of investigating them individually.}, address = {Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.}, author = {Coppola, G. and Caro, C.}, citeulike-article-id = {2646453}, citeulike-linkout-0 = {http://dx.doi.org/10.1098/rsif.2007.1338}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18252664}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18252664}, day = {6}, doi = {10.1098/rsif.2007.1338}, issn = {1742-5689}, journal = {Journal of the Royal Society, Interface / the Royal Society}, keywords = {curvedtube, device, flow, helical, hypoxia, masstransfer, numerical, oxygen, secondaryflow}, month = {September}, number = {26}, pages = {1067--1075}, posted-at = {2008-04-09 17:47:47}, priority = {0}, title = {Oxygen mass transfer in a model three-dimensional artery.}, url = {http://dx.doi.org/10.1098/rsif.2007.1338}, volume = {5}, year = {2008} }

TY - JOUR ID - coppola2008 L3 - citeulike-article-id:2646453 N2 - Arterial geometry is commonly non-planar and associated with swirling blood flow. In this study, we examine the effect of arterial three-dimensionality on the distribution of wall shear stress (WSS) and the mass transfer of oxygen from the blood to the vessel wall in a U-bend, by modelling the blood vessels as either cylindrical or helical conduits. The results show that under physiological flow conditions, three-dimensionality can reduce both the range and extent of low WSS regions and substantially increase oxygen flux through the walls. The Sherwood number and WSS distributions between the three-dimensional helical model and a human coronary artery show remarkable qualitative agreement, implying that coronary arteries may potentially be described with a relatively simple idealized three-dimensional model, characterized by a small number of well-defined geometric parameters. The flow pattern downstream of a planar bend results in separation of the Sh number and WSS effects, a finding that implies means of investigating them individually. IS - 26 JF - Journal of the Royal Society, Interface / the Royal Society SN - 1742-5689 AD - Department of Bioengineering, Imperial College London, London SW7 2AZ, UK. EP - 1075 TI - Oxygen mass transfer in a model three-dimensional artery. VL - 5 SP - 1067 KW - curvedtube KW - device KW - flow KW - helical KW - hypoxia KW - masstransfer KW - numerical KW - oxygen KW - secondaryflow AU - Coppola, G AU - Caro, C PY - 2008/09/06/ UR - http://dx.doi.org/10.1098/rsif.2007.1338 ER -