Mechanisms of frequency-specific responses of omega neuron 1 in crickets (Teleogryllus oceanicus): a polysynaptic pathway for song? Export

@article{Faulkes:2001, abstract = {In crickets (Teleogryllus oceanicus), the auditory interneuron omega neuron 1 (ON1) responds to sounds over a wide range of frequencies but is most sensitive to the frequency of conspecific songs (4.5 kHz). Response latency is longest for this same frequency. We investigate the mechanisms that might account for the longer latency of ON1 to cricket-like sounds. Intracellular recordings revealed no evidence for appropriately timed postsynaptic inhibition of ON1 that might increase its latency, nor was latency affected by picrotoxin. The onset of excitatory postsynaptic potentials (EPSPs) was delayed for 4.5 kHz stimuli compared with ultrasound stimuli, pointing to a presynaptic locus for the latency difference. When ON1 is stimulated with high frequencies, discrete, apparently unitary EPSPs can be recorded in its dendrite, and these are latency-locked to spikes recorded simultaneously in the auditory nerve. This suggests that input to ON1 from high-frequency-tuned auditory receptor neurons is monosynaptic. In agreement with this, brief ultrasound stimuli evoke a single, short-latency EPSP in ON1. In contrast, the EPSP evoked by a brief 4.5 kHz stimulus consists of an early component, similar in latency to that evoked by ultrasound and possibly evoked by ultrasound-tuned receptors, and a later, dominant component. We interpret the early peak as arising from a monosynaptic afferent pathway and the late peak from a polysynaptic afferent pathway. Multiple-peak EPSPs, with timing similar to those evoked by sound stimuli, were also evoked by electrical stimulation of the auditory nerve.}, author = {Faulkes, Z.}, citeulike-article-id = {1627611}, journal = {J Exp Biol}, keywords = {acoustic, action, afferentphysiology, and, animalphysiology, animals, antagonistspharmacology, auditory, bibtex-import, effects, excitatory, factors, female, gaba, govt, gryllidaephysiology, inhibition, interneuronsdrug, neural, neurons, non-us, pathwaysphysiology, picrotoxinpharmacology, postsynaptic, potentialsphysiology, receptors, research, sensorydrug, sound, stimulation, support, synapsesphysiology, time, vocalization}, local-url = {file://localhost/Users/jannis/Documents/Papers/2001/Faulkes/J\%20Exp\%20Biol\%202001\%20Faulkes.pdf}, month = {Apr}, number = {Pt 7}, pages = {1295--305}, posted-at = {2007-09-06 15:22:37}, priority = {2}, title = {Mechanisms of frequency-specific responses of omega neuron 1 in crickets (Teleogryllus oceanicus): a polysynaptic pathway for song?}, volume = {204}, year = {2001} }

TY - JOUR ID - Faulkes:2001 L3 - citeulike-article-id:1627611 N2 - In crickets (Teleogryllus oceanicus), the auditory interneuron omega neuron 1 (ON1) responds to sounds over a wide range of frequencies but is most sensitive to the frequency of conspecific songs (4.5 kHz). Response latency is longest for this same frequency. We investigate the mechanisms that might account for the longer latency of ON1 to cricket-like sounds. Intracellular recordings revealed no evidence for appropriately timed postsynaptic inhibition of ON1 that might increase its latency, nor was latency affected by picrotoxin. The onset of excitatory postsynaptic potentials (EPSPs) was delayed for 4.5 kHz stimuli compared with ultrasound stimuli, pointing to a presynaptic locus for the latency difference. When ON1 is stimulated with high frequencies, discrete, apparently unitary EPSPs can be recorded in its dendrite, and these are latency-locked to spikes recorded simultaneously in the auditory nerve. This suggests that input to ON1 from high-frequency-tuned auditory receptor neurons is monosynaptic. In agreement with this, brief ultrasound stimuli evoke a single, short-latency EPSP in ON1. In contrast, the EPSP evoked by a brief 4.5 kHz stimulus consists of an early component, similar in latency to that evoked by ultrasound and possibly evoked by ultrasound-tuned receptors, and a later, dominant component. We interpret the early peak as arising from a monosynaptic afferent pathway and the late peak from a polysynaptic afferent pathway. Multiple-peak EPSPs, with timing similar to those evoked by sound stimuli, were also evoked by electrical stimulation of the auditory nerve. IS - Pt 7 JF - J Exp Biol EP - 305 TI - Mechanisms of frequency-specific responses of omega neuron 1 in crickets (Teleogryllus oceanicus): a polysynaptic pathway for song? VL - 204 SP - 1295 KW - acoustic KW - action KW - afferentphysiology KW - and KW - animalphysiology KW - animals KW - antagonistspharmacology KW - auditory KW - bibtex-import KW - effects KW - excitatory KW - factors KW - female KW - gaba KW - govt KW - gryllidaephysiology KW - inhibition KW - interneuronsdrug KW - neural KW - neurons KW - non-us KW - pathwaysphysiology KW - picrotoxinpharmacology KW - postsynaptic KW - potentialsphysiology KW - receptors KW - research KW - sensorydrug KW - sound KW - stimulation KW - support KW - synapsesphysiology KW - time KW - vocalization AU - Faulkes, Z PY - 2001/Apr// ER -