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Generating samples under a Wright-Fisher neutral model of genetic variation Export

Bioinformatics (Oxford, England) In Bioinformatics, Vol. 18, No. 2. (1 February 2002), pp. 337-338.

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Summary: A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models. Availability: The source code for the program (in the language C) is available at http://home.uchicago.edu/~rhudson1/source/mksamples.html. Contact: rr-hudson@uchicago.edu 10.1093/bioinformatics/18.2.337


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