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Optical Microrheology Using Rotating Laser-Trapped Particles Export

by: Alexis I. Bishop, Timo A. Nieminen, Norman R. Heckenberg, Halina R. Dunlop
Physical Review Letters, Vol. 92, No. 19. (2004)

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laser-tweezer microrheology rotation

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We demonstrate an optical system that can apply and accurately measure the torque exerted by the trapping beam on a rotating birefringent probe particle. This allows the viscosity and surface effects within liquid media to be measured quantitatively on a micron-size scale using a trapped rotating spherical probe particle. We use the system to measure the viscosity inside a prototype cellular structure.


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