Multiple sclerosis: free light chains in cerebrospinal fluid. Export

@article{citeulike:2564860, abstract = {We found free light chains in the CSF of 18 MS patients, but not in any of 14 patients with other neurologic disease. CSF from all MS patients contained kappa and lambda chain dimers, less frequently contained light chain monomers, and never contained free gamma heavy chains. Light chains were not detected in matched serum samples. CSF from MS patients did not release free light chains from whole IgG in CSF of controls. The findings suggest that these free light chains originate in plasma cells, not from degradation of whole IgG.}, author = {Rudick, R. A. and Peter, D. R. and Bidlack, J. M. and Knutson, D. W.}, citeulike-article-id = {2564860}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/3929159}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=3929159}, issn = {0028-3878}, journal = {Neurology}, keywords = {csf, flc, ms}, month = {October}, number = {10}, pages = {1443--1449}, posted-at = {2008-03-20 05:09:38}, priority = {2}, title = {Multiple sclerosis: free light chains in cerebrospinal fluid.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/3929159}, volume = {35}, year = {1985} }

TY - JOUR ID - citeulike:2564860 L3 - citeulike-article-id:2564860 N2 - We found free light chains in the CSF of 18 MS patients, but not in any of 14 patients with other neurologic disease. CSF from all MS patients contained kappa and lambda chain dimers, less frequently contained light chain monomers, and never contained free gamma heavy chains. Light chains were not detected in matched serum samples. CSF from MS patients did not release free light chains from whole IgG in CSF of controls. The findings suggest that these free light chains originate in plasma cells, not from degradation of whole IgG. IS - 10 JF - Neurology SN - 0028-3878 EP - 1449 TI - Multiple sclerosis: free light chains in cerebrospinal fluid. VL - 35 SP - 1443 KW - csf KW - flc KW - ms AU - Rudick, RA AU - Peter, DR AU - Bidlack, JM AU - Knutson, DW PY - 1985/10// UR - http://view.ncbi.nlm.nih.gov/pubmed/3929159 ER -