Two-dimensional solid-state NMR applied to a chimeric potassium channel. Export

@article{citeulike:1155457, abstract = {Solid-state NMR (ssNMR) represents a spectroscopic method to study membrane protein structure and dynamics in lipid bilayers. We present two-dimensional correlation experiments conducted on a fully [13C,15N] labeled version of a chimeric potassium (KcsA-Kv1.3) channel. Data obtained by using two different ion concentrations suggest a structural conservation of the selectivity filter region. SsNMR experiments conducted at two different temperatures point to differential molecular dynamics of the channel.}, address = {Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, G\"{o}ttingen, Germany.}, author = {Lange, A. and Giller, K. and Pongs, O. and Becker, S. and Baldus, M.}, citeulike-article-id = {1155457}, citeulike-linkout-0 = {http://dx.doi.org/10.1080/10799890600932188}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/17118788}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=17118788}, doi = {10.1080/10799890600932188}, issn = {1079-9893}, journal = {J Recept Signal Transduct Res}, keywords = {channel, dynamics, membrane\_proteins, nmr, structure}, number = {5-6}, pages = {379--393}, posted-at = {2007-03-12 14:23:33}, priority = {2}, title = {Two-dimensional solid-state NMR applied to a chimeric potassium channel.}, url = {http://dx.doi.org/10.1080/10799890600932188}, volume = {26}, year = {2006} }

TY - JOUR ID - citeulike:1155457 L3 - citeulike-article-id:1155457 N2 - Solid-state NMR (ssNMR) represents a spectroscopic method to study membrane protein structure and dynamics in lipid bilayers. We present two-dimensional correlation experiments conducted on a fully [13C,15N] labeled version of a chimeric potassium (KcsA-Kv1.3) channel. Data obtained by using two different ion concentrations suggest a structural conservation of the selectivity filter region. SsNMR experiments conducted at two different temperatures point to differential molecular dynamics of the channel. IS - 5-6 JF - J Recept Signal Transduct Res SN - 1079-9893 AD - Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany. EP - 393 TI - Two-dimensional solid-state NMR applied to a chimeric potassium channel. VL - 26 SP - 379 KW - channel KW - dynamics KW - membrane_proteins KW - nmr KW - structure AU - Lange, A AU - Giller, K AU - Pongs, O AU - Becker, S AU - Baldus, M PY - 2006/// UR - http://dx.doi.org/10.1080/10799890600932188 ER -