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activation	179
gpcr	112
structure	89
rhodopsin	80
review	67
modeling	62
b2ar	58
dynamics	57
helix	50
transmembrane	47
theory	46
agonist	46
binding	45
ligands	41
drug	36
md	36
switch	34
pharmacology	31
membrane_proteins	31
nmr	30
crystallography	30
membrane	26
gproteins	24
dimer	20
fluorescence	18
ser	17
sequence	17
energy_landscape	15
active-state	15
pro-kink	15
fret	14
loops	14
genome	14
flexibility	14
folding	14
tm6	12
disease	12
retinal	11
mutation	11
cterm	11
binding_kinetics	10
evolution	10
toggle	10
amber	10
lipids	9
arrestin	9
tm5	9
kinetics	9
docking	9
neurokinin	9
chemokine	8
gpcrs	8
imaging	8
hbond	8
helix8	8
conformational_changes	7
cancer	7
gly	7
plasticity	7
lmc_101	7
tm3	7
w648	7
channel	7
protonation	7
icl3	7
bimane	7
ecl2	7
ionic	7
xray	6
ccr5	6
internalization	6
tm2	6
opioid	6
cys_scanning	6
cation-pi	6
thyrotropin	6
npxxy	6
dimerization	6
d250	6
spectroscopy	5
expression	5
thr	5
amine	5
dry	5
trp	5
polymorphism	5
lock	5
antagonist	4
hormone	4
nterm	4
n749	4
disorder	4
cam	4
biased_agonism	4
pathway	4
tm7	4
cholesterol	4
water	4
angiotensin	4
histamine	3
n745	3
oligomerization	3
toac	3
spin_labeling	3
cxcr1	3
webserver	3
grk	3
s542	2
chimera	2
em	2
solvation	2
lhr	2
crosslinking	2
pathways	2
5ht1a	2
tm1	2
txp	2
phylogeny	2
leukotriene	2
networks	2
tmhs	2
gaba	1
inverse_agonist	1
protein_docking	1
vasopressin	1
sequence_alignment	1
class_c	1
selectivity	1
transducin	1
tm4	1
induced_fit	1
priviledged_structures	1
b1ar	1
peptide	1
efficacy	1
membrane_protein	1
oligomers	1
kinks	1
metai	1
partial_agonists	1
binding_site	1
kinase	1