xdeupi's ligands [41 articles] Export

Recent papers added to xdeupi's library classified by the tag ligands. You can also see everyone's ligands.

	Web Server To Identify Similarity of Amino Acid Motifs to Compounds (SAAMCO) [My Copy] Journal of Chemical Information and Modeling, Vol. 48, No. 7. (1 July 2008), pp. 1524-1529. by Fergal P. Casey, Norman E. Davey, Ivan Baran, Radka S. Varekova, Denis C. Shields posted to webserver theory pharmacology ligands drug by xdeupi on 2009-10-05 18:46:59 as along with 1 person higueruelo
	Hot-Spots-Guided Receptor-Based Pharmacophores (HS-Pharm): A Knowledge-Based Approach to Identify Ligand-Anchoring Atoms in Protein Cavities and Prioritize Structure-Based Pharmacophores [My Copy] Journal of Chemical Information and Modeling, Vol. 48, No. 7. (1 July 2008), pp. 1396-1410. by Caterina Barillari, Gilles Marcou, Didier Rognan posted to theory pharmacology ligands drug docking binding b2ar agonist by xdeupi on 2009-10-05 18:45:05 as along with 3 people tbinbal superpyrin higueruelo
	Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 29. (21 July 2009), pp. 11919-11924. by Michael M. Torrice, Kiowa S. Bower, Henry A. Lester, Dennis A. Dougherty posted to ligands cation-pi binding activation by xdeupi on 2009-08-28 12:57:57 as along with 1 person paulschlesinger
	Allosteric modulation of muscarinic acetylcholine receptors. [My Copy] Current neuropharmacology, Vol. 5, No. 3. (September 2007), pp. 157-167. by K. J. Gregory, P. M. Sexton, A. Christopoulos posted to activation agonist binding kinetics ligands pharmacology by xdeupi on 2009-07-20 18:21:37 as
	Validity of (−)-[<sup>3</sup>H]-CGP 12177A as a radioligand for the 'putative <i>β</i><sub>4</sub>-adrenoceptor' in rat atrium [My Copy] British Journal of Pharmacology, Vol. 123, No. 3. (1998), pp. 371-380. by Doreen Sarsero, Peter Molenaar, Alberto J. Kaumann posted to b1ar ligands pharmacology by xdeupi on 2009-06-10 13:56:13 as
	Sequence-Derived Three-Dimensional Pharmacophore Models for G-Protein-Coupled Receptors and Their Application in Virtual Screening [My Copy] Journal of Medicinal Chemistry, Vol. 0, No. 0. (0000) by Thomas Klabunde, Clemens Giegerich, Andreas Evers posted to agonist antagonist binding drug ligands modeling pharmacology by xdeupi on 2009-05-06 09:59:59 as along with 1 person reyez
	Revisiting Automated G-Protein Coupled Receptor Modeling: The Benefit of Additional Template Structures for a Neurokinin-1 Receptor Model. [My Copy] Journal of medicinal chemistry (28 April 2009) by Benny Kneissl, Bettina Leonhardt, Andreas Hildebrandt, Christofer S S. Tautermann posted to docking gpcr ligands modeling neurokinin by xdeupi on 2009-05-06 09:47:25 as along with 1 person reyez
	A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. [My Copy] Structure (London, England : 1993), Vol. 16, No. 6. (June 2008), pp. 897-905. by M. A. Hanson, V. Cherezov, M. T. Griffith, et al.C. B. Roth, V. P. Jaakola, E. Y. Chien, J. Velasquez, P. Kuhn, R. C. Stevens posted to b2ar cholesterol crystallography drug ligands structure by xdeupi on 2009-01-09 12:05:17 as along with 1 person and 1 group merj LabCompMed
	Physiological relevance of GPCR oligomerization and its impact on drug discovery. [My Copy] Drug discovery today, Vol. 13, No. 23-24. (14 December 2008), pp. 1059-1066. by Rosemarie Panetta, Michael T. Greenwood posted to dimer disease drug gpcr ligands pharmacology review by xdeupi on 2008-10-16 09:57:50 as along with 1 person guhjy
	Fluorescent GPCR ligands as new tools in pharmacology. [My Copy] Current medicinal chemistry, Vol. 15, No. 21. (2008), pp. 2132-2143. by K. Kuder, K. Kieć-Kononowicz posted to activation agonist binding drug fluorescence imaging ligands by xdeupi on 2008-10-15 10:30:17 as
	The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist [My Copy] Science (2 October 2008), 1164772. by Veli-Pekka Jaakola, Mark T. Griffith, Michael A. Hanson, et al.Vadim Cherezov, Ellen Y. Chien, Robert J. Lane, Adriaan P. Ijzerman, Raymond C. Stevens posted to binding crystallography docking gpcr ligands structure xray by xdeupi on 2008-10-15 10:02:26 as along with 1 person and 1 group cen4ik LabCompMed
	Structure of a β1-adrenergic G-protein-coupled receptor [My Copy] Nature (25 June 2008) by Tony Warne, Maria J. Serrano-Vega, Jillian G. Baker, et al.Rouslan Moukhametzianov, Patricia C. Edwards, Richard Henderson, Andrew G. W. Leslie, Christopher G. Tate, Gebhard F. X. Schertler posted to b2ar binding docking drug ligands structure xray by xdeupi on 2008-09-16 10:15:17 as along with 2 people and 2 groups merj TonyIvetac LabCompMed McCammon
	Chemogenomic approaches to rational drug design [My Copy] Br J Pharmacol, Vol. 152, No. 1. (29 May 2007), pp. 38-52. by D. Rognan posted to agonist binding drug ligands pharmacology priviledged_structures by xdeupi on 2008-03-28 15:54:47 as along with 4 people and 3 groups jmrivort jerome_ucsf_slb guhjy tjimenez LabCompMed G-quadruplex Supramolecular
	Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor. [My Copy] J Biol Chem, Vol. 274, No. 31. (30 July 1999), pp. 21867-21872. by A. Marjamäki, H. Frang, M. Pihlavisto, et al.A. M. Hoffrén, T. Salminen, M. S. Johnson, J. Kallio, J. A. Javitch, M. Scheinin posted to activation binding cys_scanning drug ligands tm5 by xdeupi on 2008-03-07 15:14:37 as along with 1 group LabCompMed
	beta-Arrestin-biased Agonism at the beta2-Adrenergic Receptor. [My Copy] J Biol Chem, Vol. 283, No. 9. (29 February 2008), pp. 5669-5676. by M. T. Drake, J. D. Violin, E. J. Whalen, J. W. Wisler, S. K. Shenoy, R. J. Lefkowitz posted to activation agonist arrestin b2ar biased_agonism drug gproteins imaging internalization ligands pharmacology by xdeupi on 2008-02-27 10:39:07 as along with 1 group LabCompMed
	Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands [My Copy] J. Biol. Chem., Vol. 282, No. 35. (31 August 2007), pp. 25677-25686. by Vimesh A. Avlani, Karen J. Gregory, Craig J. Morton, Michael W. Parker, Patrick M. Sexton, Arthur Christopoulos posted to activation binding ecl2 ligands loops structure by xdeupi on 2007-06-29 21:12:42 as along with 1 group LabCompMed
	Chromophore Channeling in the G-Protein Coupled Receptor Rhodopsin. [My Copy] J Am Chem Soc (15 May 2007) by Ting Wang, Yong Duan posted to activation agonist amber binding ligands md modeling rhodopsin by xdeupi on 2007-05-21 10:04:04 as along with 1 group LabCompMed
	"Phenotypic" pharmacology: the influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology. [My Copy] Biochem Pharmacol, Vol. 73, No. 6. (15 March 2007), pp. 737-751. by C. P. Nelson, R. A. Challiss posted to agonist gpcr ligands pharmacology by xdeupi on 2007-04-10 18:54:26 as along with 1 person and 2 groups Fritz neurolit LabCompMed
	Bioluminescence resonance energy transfer as a screening assay: Focus on partial and inverse agonism. [My Copy] J Biomol Screen, Vol. 12, No. 1. (February 2007), pp. 41-49. by L. Elster, C. Elling, A. Heding posted to activation agonist b2ar fret ligands by xdeupi on 2007-04-10 18:50:15 as along with 1 group LabCompMed
	Subclassification and nomenclature of alpha- and beta-adrenoceptors. [My Copy] Curr Top Med Chem, Vol. 7, No. 2. (2007), pp. 129-134. by J. P. Hieble posted to agonist b2ar drug genome ligands pharmacology review by xdeupi on 2007-03-12 14:33:19 as along with 1 group LabCompMed
	Recent advances in identification and characterization of beta-adrenoceptor agonists and antagonists. [My Copy] Curr Top Med Chem, Vol. 7, No. 2. (2007), pp. 207-216. by J. P. Hieble posted to agonist b2ar drug ligands pharmacology by xdeupi on 2007-03-12 14:32:04 as along with 1 group LabCompMed
	Drugs, their targets and the nature and number of drug targets [My Copy] Nature Reviews Drug Discovery, Vol. 5, No. 10., pp. 821-834. by Peter Imming, Christian Sinning, Achim Meyer posted to review ligands gpcr genome drug by xdeupi on 2007-01-22 17:55:08 as along with 4 people and 1 group kuhn massivemayhem Ao_Li2007 yaredo LabCompMed
	Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor. [My Copy] J Biol Chem, Vol. 280, No. 41. (14 October 2005), pp. 34849-34858. by S. J. Han, F. F. Hamdan, S. K. Kim, et al.K. A. Jacobson, L. M. Bloodworth, B. Li, J. Wess posted to ligands cation-pi binding agonist by xdeupi on 2007-01-15 16:08:15 as along with 1 group LabCompMed
	Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV and -VI. [My Copy] Mol Pharmacol (14 December 2006) by Mette M M. Rosenkilde, Michael B B. Andersen, Rie Nygaard, Thomas M M. Frimurer, Thue W W. Schwartz posted to ligands ionic chemokine cation-pi agonist activation by xdeupi on 2007-01-11 16:06:35 as along with 1 group LabCompMed
	The Cationminus signpi Interaction. [My Copy] Chem Rev, Vol. 97, No. 5. (5 August 1997), pp. 1303-1324. by Jennifer C. Ma, Dennis A. Dougherty posted to trp ligands histamine cation-pi binding b2ar by xdeupi on 2007-01-11 14:28:54 as along with 1 group LabCompMed
	GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors. [My Copy] Curr Top Med Chem, Vol. 6, No. 13. (2006), pp. 1319-1333. by M. M. Rosenkilde, T. W. Schwartz posted to modeling ligands ionic chemokine binding agonist by xdeupi on 2007-01-10 14:45:13 as along with 1 group LabCompMed
	I want a new drug: G-protein-coupled receptors in drug development. [My Copy] Drug Discov Today, Vol. 11, No. 11-12. (June 2006), pp. 481-493. by S. Schlyer, R. Horuk posted to cancer drug gpcr ligands pharmacology review by xdeupi on 2006-11-04 12:41:53 as along with 1 person and 1 group zimbo1 LabCompMed
	dummy [My Copy] by Dummy posted to 5ht1a activation agonist amber amine arrestin b2ar bimane binding cam ccr5 channel chemokine chimera crystallography cterm cxcr1 d250 dimer disease drug dry dynamics ecl2 evolution expression fluorescence folding fret genome gly gpcr gproteins hbond helix helix8 histamine hormone icl3 imaging internalization ionic leukotriene lhr ligands lipids lock loops md membrane modeling mutation n745 n749 nmr npxxy nterm opioid pharmacology polymorphism pro-kink protonation review rhodopsin s542 sequence ser spin_labeling structure switch thr thyrotropin tm2 tm3 tm5 tm6 tm7 toggle transmembrane trp txp w648 by xdeupi on 2006-10-30 12:30:16 as along with 2 people and 1 group jessicaopacic ivanrt LabCompMed
	Modeling and active site refinement for G protein-coupled receptors: application to the beta-2 adrenergic receptor. [My Copy] J Comput Aided Mol Des (13 October 2006) by Stanley R. Krystek, S R. Kimura, Andrew J. Tebben posted to b2ar binding drug ligands modeling pharmacology by xdeupi on 2006-10-27 09:43:03 as along with 1 person and 1 group daevans LabCompMed
	A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. [My Copy] Proc Natl Acad Sci U S A, Vol. 103, No. 30. (25 July 2006), pp. 11288-11293. by S. B. Liggett, J. Mialet-Perez, S. Thaneemit-Chen, et al.S. A. Weber, S. M. Greene, D. Hodne, B. Nelson, J. Morrison, M. J. Domanski, L. E. Wagoner, W. T. Abraham, J. L. Anderson, J. F. Carlquist, H. J. Krause-Steinrauf, L. C. Lazzeroni, J. D. Port, P. W. Lavori, M. R. Bristow posted to b2ar disease drug genome helix8 ligands polymorphism by xdeupi on 2006-09-05 11:38:25 as along with 1 group LabCompMed
	Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation. [My Copy] J Biol Chem, Vol. 281, No. 26. (30 June 2006), pp. 18120-18125. by B. Behr, C. Hoffmann, G. Ottolina, K. N. Klotz posted to activation agonist b2ar binding drug ligands modeling mutation pharmacology structure by xdeupi on 2006-09-05 11:05:20 as along with 1 group LabCompMed
	Determining the Potency and Molecular Mechanism of Action of Insurmountable Antagonists. [My Copy] J Pharmacol Exp Ther (20 July 2006) by Terry P P. Kenakin, Stephen Jenkinson, Christian Watson posted to activation drug ligands agonist pharmacology by xdeupi on 2006-09-05 09:51:58 as along with 1 group LabCompMed
	GPCR agonists and antagonists in the clinic. [My Copy] Med Chem, Vol. 1, No. 4. (July 2005), pp. 405-421. by J. D. Tyndall, R. Sandilya posted to agonist drug gpcr ligands pharmacology by xdeupi on 2006-07-24 10:18:01 as along with 1 group LabCompMed
	Data-Driven Analysis in Drug Discovery [My Copy] Journal of Receptors and Signal Transduction, Vol. 26, No. 4. (August 2006), pp. 299-327. by Terry Kenakin posted to agonist binding drug ligands pharmacology by xdeupi on 2006-07-17 16:28:05 as along with 1 group LabCompMed
	Changes in interhelical hydrogen bonding upon rhodopsin activation. [My Copy] J Mol Biol, Vol. 347, No. 4. (8 April 2005), pp. 803-812. by A. B. Patel, E. Crocker, P. J. Reeves, et al.E. V. Getmanova, M. Eilers, H. G. Khorana, S. O. Smith posted to activation b2ar binding hbond helix ligands nmr pro-kink rhodopsin ser structure switch tm5 tm6 toggle by xdeupi on 2006-06-01 13:51:11 as along with 1 group LabCompMed
	Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines. [My Copy] J Med Chem, Vol. 49, No. 5. (9 March 2006), pp. 1706-1719. by H. Xhaard, V. V. Rantanen, T. Nyrönen, M. S. Johnson posted to agonist b2ar binding gpcr ligands modeling by xdeupi on 2006-03-06 10:11:30 as along with 1 group LabCompMed
	The identification of ligands at orphan G-protein coupled receptors. [My Copy] Annu Rev Pharmacol Toxicol, Vol. 44 (2004), pp. 43-66. by A. Wise, S. C. Jupe, S. Rees posted to drug gpcr ligands by xdeupi on 2006-03-01 16:35:26 as along with 1 group LabCompMed
	A chemogenomic analysis of the transmembrane binding cavity of human G-protein-coupled receptors. [My Copy] Proteins, Vol. 62, No. 2. (1 February 2006), pp. 509-538. by J. S. Surgand, J. Rodrigo, E. Kellenberger, D. Rognan posted to binding gpcr ligands transmembrane by xdeupi on 2006-03-01 16:33:01 as along with 1 person and 1 group naweill LabCompMed
	Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states. [My Copy] J Biol Chem, Vol. 279, No. 1. (2 January 2004), pp. 686-691. by G. Swaminath, Y. Xiang, T. W. Lee, J. Steenhuis, C. Parnot, B. K. Kobilka posted to activation agonist b2ar binding ligands tm6 by xdeupi on 2005-12-16 10:19:18 as along with 1 person and 1 group jddowney LabCompMed
	New concepts in drug discovery: collateral efficacy and permissive antagonism. [My Copy] Nat Rev Drug Discov, Vol. 4, No. 11. (November 2005), pp. 919-927. by T. Kenakin posted to activation agonist ccr5 gpcr ligands by xdeupi on 2005-11-04 21:57:24 as along with 1 group LabCompMed
	Design, synthesis and pharmacological evaluation of 5-hydroxytryptamine(1a) receptor ligands to explore the three-dimensional structure of the receptor. [My Copy] Mol Pharmacol, Vol. 62, No. 1. (July 2002), pp. 15-21. by M. L. López-Rodríguez, B. Vicente, X. Deupi, et al.S. Barrondo, M. Olivella, M. J. Morcillo, B. Behamú, J. A. Ballesteros, J. Sallés, L. Pardo posted to 5ht1a ligands by xdeupi on 2005-10-25 03:16:43 as along with 1 group LabCompMed

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activation	173
gpcr	112
structure	89
rhodopsin	79
review	65
modeling	62
b2ar	58
dynamics	56
helix	50
transmembrane	47
agonist	46
binding	45
theory	44
ligands	41
drug	36
md	35
switch	34
membrane_proteins	31
pharmacology	31
crystallography	30
nmr	30
membrane	26
gproteins	24
dimer	20
fluorescence	18
sequence	17
ser	17
active-state	15
pro-kink	15
folding	14
fret	14
genome	14
loops	14
flexibility	13
disease	12
tm6	12
cterm	11
mutation	11
retinal	11
amber	10
energy_landscape	10
evolution	10
toggle	10
arrestin	9
docking	9
kinetics	9
lipids	9
neurokinin	9
tm5	9
chemokine	8
gpcrs	8
hbond	8
helix8	8
imaging	8
bimane	7
cancer	7
channel	7
ecl2	7
gly	7
icl3	7
ionic	7
lmc_101	7
plasticity	7
protonation	7
tm3	7
w648	7
cation-pi	6
ccr5	6
conformational_changes	6
cys_scanning	6
d250	6
internalization	6
npxxy	6
opioid	6
thyrotropin	6
tm2	6
xray	6
amine	5
binding_kinetics	5
dimerization	5
dry	5
expression	5
lock	5
polymorphism	5
spectroscopy	5
thr	5
trp	5
angiotensin	4
antagonist	4
biased_agonism	4
cam	4
cholesterol	4
disorder	4
hormone	4
n749	4
nterm	4
pathway	4
tm7	4
water	4
cxcr1	3
grk	3
histamine	3
n745	3
oligomerization	3
spin_labeling	3
toac	3
webserver	3
5ht1a	2
chimera	2
crosslinking	2
em	2
leukotriene	2
lhr	2
networks	2
pathways	2
phylogeny	2
s542	2
solvation	2
tm1	2
tmhs	2
txp	2
b1ar	1
binding_site	1
class_c	1
efficacy	1
gaba	1
induced_fit	1
inverse_agonist	1
kinase	1
kinks	1
metai	1
oligomers	1
peptide	1
priviledged_structures	1
protein_docking	1
selectivity	1
sequence_alignment	1
tm4	1
transducin	1
vasopressin	1

xdeupi's ligands [41 articles] Export

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