Mediator and the mechanism of transcriptional activation. Export

@article{citeulike:1041365, abstract = {Mediator was discovered because of its activity in a yeast RNA polymerase II (pol II) transcription system - it is needed for the system to respond to a transcriptional activator. Mediator is the central link in the enhancer-->activator-->Mediator-->pol II-->promoter pathway. The transduction of regulatory signals through this pathway is crucial for transcription of almost all pol II promoters in all eukaryote organisms.}, address = {Department of Structural Biology, Stanford School of Medicine, Stanford, CA 94305, USA. kornberg@stanford.edu}, author = {Kornberg, R. D.}, citeulike-article-id = {1041365}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tibs.2005.03.011}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0968000405000836}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/15896740}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=15896740}, doi = {10.1016/j.tibs.2005.03.011}, issn = {0968-0004}, journal = {Trends Biochem Sci}, keywords = {activation, activator, enhancer, kornberg, mediator, repressor, review, transcription}, month = {May}, number = {5}, pages = {235--239}, posted-at = {2007-01-14 20:39:46}, priority = {2}, title = {Mediator and the mechanism of transcriptional activation.}, url = {http://dx.doi.org/10.1016/j.tibs.2005.03.011}, volume = {30}, year = {2005} }

TY - JOUR ID - citeulike:1041365 L3 - citeulike-article-id:1041365 N2 - Mediator was discovered because of its activity in a yeast RNA polymerase II (pol II) transcription system - it is needed for the system to respond to a transcriptional activator. Mediator is the central link in the enhancer-->activator-->Mediator-->pol II-->promoter pathway. The transduction of regulatory signals through this pathway is crucial for transcription of almost all pol II promoters in all eukaryote organisms. IS - 5 JF - Trends Biochem Sci SN - 0968-0004 AD - Department of Structural Biology, Stanford School of Medicine, Stanford, CA 94305, USA. kornberg@stanford.edu EP - 239 TI - Mediator and the mechanism of transcriptional activation. VL - 30 SP - 235 KW - activation KW - activator KW - enhancer KW - kornberg KW - mediator KW - repressor KW - review KW - transcription AU - Kornberg, RD PY - 2005/05// UR - http://dx.doi.org/10.1016/j.tibs.2005.03.011 ER -