DNA methylation in health and disease.

@article{citeulike:2703338, abstract = {DNA methylation has recently moved to centre stage in the aetiology of human neurodevelopmental syndromes such as the fragile X, ICF and Rett syndromes. These diseases result from the misregulation of genes that occurs with the loss of appropriate epigenetic controls during neuronal development. Recent advances have connected DNA methylation to chromatin-remodelling enzymes, and understanding this link will be central to the design of new therapeutic tools.}, address = {Epigenetic Gene Regulation and Cancer Section, NCI, NIH, Building 41, 41 Library Drive, Bethesda, Maryland 20892-5431, USA.}, author = {Robertson, K. D. and Wolffe, A. P. }, citeulike-article-id = {2703338}, doi = {10.1038/35049533}, issn = {1471-0056}, journal = {Nature reviews. Genetics}, month = {October}, number = {1}, pages = {11--19}, posted-at = {2008-04-23 00:36:21}, priority = {2}, title = {DNA methylation in health and disease.}, url = {http://dx.doi.org/10.1038/35049533}, volume = {1}, year = {2000} }

TY - JOUR ID - citeulike:2703338 L3 - citeulike-article-id:2703338 TI - DNA methylation in health and disease. JF - Nature reviews. Genetics VL - 1 IS - 1 SP - 11 EP - 19 AD - Epigenetic Gene Regulation and Cancer Section, NCI, NIH, Building 41, 41 Library Drive, Bethesda, Maryland 20892-5431, USA. SN - 1471-0056 N2 - DNA methylation has recently moved to centre stage in the aetiology of human neurodevelopmental syndromes such as the fragile X, ICF and Rett syndromes. These diseases result from the misregulation of genes that occurs with the loss of appropriate epigenetic controls during neuronal development. Recent advances have connected DNA methylation to chromatin-remodelling enzymes, and understanding this link will be central to the design of new therapeutic tools. AU - Robertson, KD AU - Wolffe, AP PY - 2000/10// UR - http://dx.doi.org/10.1038/35049533 ER -