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The spanish connection: transcription and mRNA processing get even closer. Export

Cell, Vol. 120, No. 2. (28 January 2005), pp. 163-166.

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cap connection coupling mrna polya processing splicing transcription

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The synthesis of mRNA by RNA polymerase II appears coupled to numerous RNA-processing events, based on physical or functional connections revealed by biochemical or genetic tests. New findings were presented at a recent meeting in Spain that begin to illuminate the mechanisms underlying the connections between mRNA processing and specific steps in transcription (initiation, elongation, and termination) as well as recombination.


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