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Identification of a new prostate cancer susceptibility locus on chromosome 8q24 Export

Nature Genetics, Vol. 41, No. 10. (20 September 2009), pp. 1055-1057.

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8q24 cgems mapping prostate_cancer

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We report a genome-wide association study in 10,286 cases and 9,135 controls of European ancestry in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. We identify a new association with prostate cancer risk on chromosome 8q24 (rs620861, P = 1.3 |[times]| 10|[minus]|10, heterozygote OR = 1.17, 95% CI 1.10–1.24; homozygote OR = 1.33, 95% CI 1.21–1.45).


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