Searching for a baseline: functional imaging and the resting human brain.

@article{citeulike:790119, abstract = {Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function.}, address = {The Mallinckrodt Institute of Radiology, Washington University, St Louis, Missouri 63110, USA.}, author = {Gusnard, D. A. and Raichle, M. E. and Raichle, M. E.}, citeulike-article-id = {790119}, doi = {10.1038/35094500}, issn = {1471-003X}, journal = {Nat Rev Neurosci}, keywords = {baseline, default-mode, resting-state}, month = {October}, number = {10}, pages = {685--694}, posted-at = {2006-09-11 10:44:23}, priority = {0}, title = {Searching for a baseline: functional imaging and the resting human brain.}, url = {http://dx.doi.org/10.1038/35094500}, volume = {2}, year = {2001} }

TY - JOUR ID - citeulike:790119 L3 - citeulike-article-id:790119 N2 - Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function. IS - 10 JF - Nat Rev Neurosci SN - 1471-003X AD - The Mallinckrodt Institute of Radiology, Washington University, St Louis, Missouri 63110, USA. EP - 694 TI - Searching for a baseline: functional imaging and the resting human brain. VL - 2 SP - 685 KW - baseline KW - default-mode KW - resting-state AU - Gusnard, DA AU - Raichle, ME AU - Raichle, ME PY - 2001/10// UR - http://dx.doi.org/10.1038/35094500 ER -