Interregional connectivity to primary motor cortex revealed using MRI resting state images. Export

@article{citeulike:790122, abstract = {The topographic organization of cortical neurons is traditionally examined using histological procedures. Functional magnetic resonance imaging (fMRI) offers the potential noninvasively to detect interregional connectivity of human brain. In the brain, there is spontaneous firing of neurons even in the resting state. Such spontaneous firing will increase local blood flow, cause MRI signal fluctuations, and affect remotely located neurons through the efferent output. By calculating covariance of each voxel referenced to the time course of a selected brain region, it is possible to detect the neurons connected to the selected region. Using this covariance method, neural connectivity to primary motor cortex was assessed during a resting state in six healthy right-handed volunteers. This interregional connectivity is similar to connectivity established by other anatomical, histochemical, and physiological techniques. This method may offer in vivo noninvasive measurements of neural projections.}, address = {Research Imaging Center and Department of Radiology, University of Texas Health Science Center, San Antonio 78284-6240, USA. xiong@uthscsa.edu}, author = {Xiong, J. and Parsons, L. M. and Gao, J. H. and Fox, P. T.}, citeulike-article-id = {790122}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/10524607}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=10524607}, issn = {1065-9471}, journal = {Hum Brain Mapp}, keywords = {functional-connectivity, motor-cortex, resting-state}, number = {2-3}, pages = {151--156}, posted-at = {2007-01-27 09:24:39}, priority = {3}, title = {Interregional connectivity to primary motor cortex revealed using MRI resting state images.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/10524607}, volume = {8}, year = {1999} }

TY - JOUR ID - citeulike:790122 L3 - citeulike-article-id:790122 N2 - The topographic organization of cortical neurons is traditionally examined using histological procedures. Functional magnetic resonance imaging (fMRI) offers the potential noninvasively to detect interregional connectivity of human brain. In the brain, there is spontaneous firing of neurons even in the resting state. Such spontaneous firing will increase local blood flow, cause MRI signal fluctuations, and affect remotely located neurons through the efferent output. By calculating covariance of each voxel referenced to the time course of a selected brain region, it is possible to detect the neurons connected to the selected region. Using this covariance method, neural connectivity to primary motor cortex was assessed during a resting state in six healthy right-handed volunteers. This interregional connectivity is similar to connectivity established by other anatomical, histochemical, and physiological techniques. This method may offer in vivo noninvasive measurements of neural projections. IS - 2-3 JF - Hum Brain Mapp SN - 1065-9471 AD - Research Imaging Center and Department of Radiology, University of Texas Health Science Center, San Antonio 78284-6240, USA. xiong@uthscsa.edu EP - 156 TI - Interregional connectivity to primary motor cortex revealed using MRI resting state images. VL - 8 SP - 151 KW - functional-connectivity KW - motor-cortex KW - resting-state AU - Xiong, J AU - Parsons, LM AU - Gao, JH AU - Fox, PT PY - 1999/// UR - http://view.ncbi.nlm.nih.gov/pubmed/10524607 ER -