Molecular imaging of vessels in mouse models of disease. Export

@article{citeulike:4292597, abstract = {Vascular imaging of angiogenesis in mouse models of disease requires multi modal imaging hardware capable of targeting both structure and function at different physical scales. The three dimensional (3D) structure and function vascular information allows for accurate differentiation between biological processes. For example, image analysis of vessel development in angiogenesis vs. arteriogenesis enables more accurate detection of biological variation between subjects and more robust and reliable diagnosis of disease. In the recent years a number of micro imaging modalities have emerged in the field as preferred means for this purpose. They provide 3D volumetric data suitable for analysis, quantification, validation, and visualization of results in animal models. This review highlights the capabilities of microCT, ultrasound and microPET for multimodal imaging of angiogenesis and molecular vascular targets in a mouse model of tumor angiogenesis. The basic principles of the imaging modalities are described and experimental results are presented.}, author = {Zagorchev, Lyubomir and Mulligan-Kehoe, Mary J J.}, citeulike-article-id = {4292597}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ejrad.2009.01.053}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19304428}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19304428}, day = {20}, doi = {10.1016/j.ejrad.2009.01.053}, issn = {1872-7727}, journal = {European journal of radiology}, keywords = {angiogenesis, angiography, animal-models, imaging}, month = {March}, posted-at = {2009-04-08 21:49:53}, priority = {5}, title = {Molecular imaging of vessels in mouse models of disease.}, url = {http://dx.doi.org/10.1016/j.ejrad.2009.01.053}, year = {2009} }

TY - JOUR ID - citeulike:4292597 L3 - citeulike-article-id:4292597 N2 - Vascular imaging of angiogenesis in mouse models of disease requires multi modal imaging hardware capable of targeting both structure and function at different physical scales. The three dimensional (3D) structure and function vascular information allows for accurate differentiation between biological processes. For example, image analysis of vessel development in angiogenesis vs. arteriogenesis enables more accurate detection of biological variation between subjects and more robust and reliable diagnosis of disease. In the recent years a number of micro imaging modalities have emerged in the field as preferred means for this purpose. They provide 3D volumetric data suitable for analysis, quantification, validation, and visualization of results in animal models. This review highlights the capabilities of microCT, ultrasound and microPET for multimodal imaging of angiogenesis and molecular vascular targets in a mouse model of tumor angiogenesis. The basic principles of the imaging modalities are described and experimental results are presented. JF - European journal of radiology SN - 1872-7727 TI - Molecular imaging of vessels in mouse models of disease. KW - angiogenesis KW - angiography KW - animal-models KW - imaging AU - Zagorchev, Lyubomir AU - Mulligan-Kehoe, Mary J PY - 2009/03/20/ UR - http://dx.doi.org/10.1016/j.ejrad.2009.01.053 ER -