Starch as a major integrator in the regulation of plant growth. Export

@article{citeulike:4909148, abstract = {Rising demand for food and bioenergy makes it imperative to breed for increased crop yield. Vegetative plant growth could be driven by resource acquisition or developmental programs. Metabolite profiling in 94 Arabidopsis accessions revealed that biomass correlates negatively with many metabolites, especially starch. Starch accumulates in the light and is degraded at night to provide a sustained supply of carbon for growth. Multivariate analysis revealed that starch is an integrator of the overall metabolic response. We hypothesized that this reflects variation in a regulatory network that balances growth with the carbon supply. Transcript profiling in 21 accessions revealed coordinated changes of transcripts of more than 70 carbon-regulated genes and identified 2 genes (myo-inositol-1-phosphate synthase, a Kelch-domain protein) whose transcripts correlate with biomass. The impact of allelic variation at these 2 loci was shown by association mapping, identifying them as candidate lead genes with the potential to increase biomass production.}, author = {Sulpice, Ronan and Pyl, Eva-Theresa T. and Ishihara, Hirofumi and Trenkamp, Sandra and Steinfath, Matthias and Witucka-Wall, Hanna and Gibon, Yves and Usadel, Bj\"{o}rn and Poree, Fabien and Piques, Maria Concei\c{c}\~{a}o C. and Von Korff, Maria and Steinhauser, Marie Caroline C. and Keurentjes, Joost J. and Guenther, Manuela and Hoehne, Melanie and Selbig, Joachim and Fernie, Alisdair R. and Altmann, Thomas and Stitt, Mark}, citeulike-article-id = {4909148}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0903478106}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19506259}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19506259}, day = {8}, doi = {10.1073/pnas.0903478106}, issn = {1091-6490}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {arabidopsis, association\_mapping, heterosis, plants, regulation, starch}, month = {June}, posted-at = {2009-06-19 17:19:56}, priority = {2}, title = {Starch as a major integrator in the regulation of plant growth.}, url = {http://dx.doi.org/10.1073/pnas.0903478106}, year = {2009} }

TY - JOUR ID - citeulike:4909148 L3 - citeulike-article-id:4909148 N2 - Rising demand for food and bioenergy makes it imperative to breed for increased crop yield. Vegetative plant growth could be driven by resource acquisition or developmental programs. Metabolite profiling in 94 Arabidopsis accessions revealed that biomass correlates negatively with many metabolites, especially starch. Starch accumulates in the light and is degraded at night to provide a sustained supply of carbon for growth. Multivariate analysis revealed that starch is an integrator of the overall metabolic response. We hypothesized that this reflects variation in a regulatory network that balances growth with the carbon supply. Transcript profiling in 21 accessions revealed coordinated changes of transcripts of more than 70 carbon-regulated genes and identified 2 genes (myo-inositol-1-phosphate synthase, a Kelch-domain protein) whose transcripts correlate with biomass. The impact of allelic variation at these 2 loci was shown by association mapping, identifying them as candidate lead genes with the potential to increase biomass production. JF - Proceedings of the National Academy of Sciences of the United States of America SN - 1091-6490 TI - Starch as a major integrator in the regulation of plant growth. KW - arabidopsis KW - association_mapping KW - heterosis KW - plants KW - regulation KW - starch AU - Sulpice, Ronan AU - Pyl, Eva-Theresa AU - Ishihara, Hirofumi AU - Trenkamp, Sandra AU - Steinfath, Matthias AU - Witucka-Wall, Hanna AU - Gibon, Yves AU - Usadel, Björn AU - Poree, Fabien AU - Piques, Maria Conceição AU - Von Korff, Maria AU - Steinhauser, Marie Caroline AU - Keurentjes, Joost AU - Guenther, Manuela AU - Hoehne, Melanie AU - Selbig, Joachim AU - Fernie, Alisdair AU - Altmann, Thomas AU - Stitt, Mark PY - 2009/06/08/ UR - http://dx.doi.org/10.1073/pnas.0903478106 ER -