Prediction of plant microRNA targets. Export

@article{citeulike:620386, abstract = {We predict regulatory targets for 14 Arabidopsis microRNAs (miRNAs) by identifying mRNAs with near complementarity. Complementary sites within predicted targets are conserved in rice. Of the 49 predicted targets, 34 are members of transcription factor gene families involved in developmental patterning or cell differentiation. The near-perfect complementarity between plant miRNAs and their targets suggests that many plant miRNAs act similarly to small interfering RNAs and direct mRNA cleavage. The targeting of developmental transcription factors suggests that many plant miRNAs function during cellular differentiation to clear key regulatory transcripts from daughter cell lineages.}, address = {Whitehead Institute for Biomedical Research, 9 Cambridge Center, MA 02142, USA.}, author = {Rhoades, M. W. and Reinhart, B. J. and Lim, L. P. and Burge, C. B. and Bartel, B. and Bartel, D. P.}, citeulike-article-id = {620386}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12202040}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12202040}, issn = {0092-8674}, journal = {Cell}, keywords = {arabidopsis, comparative\_study, data\_mining, method, mirna, plants}, month = {August}, number = {4}, pages = {513--520}, posted-at = {2007-07-01 17:13:13}, priority = {2}, title = {Prediction of plant microRNA targets.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12202040}, volume = {110}, year = {2002} }

TY - JOUR ID - citeulike:620386 L3 - citeulike-article-id:620386 N2 - We predict regulatory targets for 14 Arabidopsis microRNAs (miRNAs) by identifying mRNAs with near complementarity. Complementary sites within predicted targets are conserved in rice. Of the 49 predicted targets, 34 are members of transcription factor gene families involved in developmental patterning or cell differentiation. The near-perfect complementarity between plant miRNAs and their targets suggests that many plant miRNAs act similarly to small interfering RNAs and direct mRNA cleavage. The targeting of developmental transcription factors suggests that many plant miRNAs function during cellular differentiation to clear key regulatory transcripts from daughter cell lineages. IS - 4 JF - Cell SN - 0092-8674 AD - Whitehead Institute for Biomedical Research, 9 Cambridge Center, MA 02142, USA. EP - 520 TI - Prediction of plant microRNA targets. VL - 110 SP - 513 KW - arabidopsis KW - comparative_study KW - data_mining KW - method KW - mirna KW - plants AU - Rhoades, MW AU - Reinhart, BJ AU - Lim, LP AU - Burge, CB AU - Bartel, B AU - Bartel, DP PY - 2002/08/23/ UR - http://view.ncbi.nlm.nih.gov/pubmed/12202040 ER -