Cancer: Three birds with one stone Export

@article{citeulike:5241493, abstract = {The core domain of the p53 protein has been found to affect microRNA processing — its third known antitumour activity. Most cancerous p53 mutations affect this domain and may abolish all tumour-suppressor functions. The p53 protein is a major tumour suppressor. The gene that encodes it (TP53) is mutated in about half of human cancers, and most remaining tumours find other ways to inactivate the p53 pathway1.}, author = {Toledo, Franck and Bardot, Boris}, citeulike-article-id = {5241493}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/460466a}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/460466a}, day = {22}, doi = {10.1038/460466a}, issn = {0028-0836}, journal = {Nature}, keywords = {biomedical, cancer, p53}, month = {July}, number = {7254}, pages = {466--467}, posted-at = {2009-10-27 03:21:44}, priority = {2}, publisher = {Nature Publishing Group}, title = {Cancer: Three birds with one stone}, url = {http://dx.doi.org/10.1038/460466a}, volume = {460}, year = {2009} }

TY - JOUR ID - citeulike:5241493 L3 - citeulike-article-id:5241493 N2 - The core domain of the p53 protein has been found to affect microRNA processing — its third known antitumour activity. Most cancerous p53 mutations affect this domain and may abolish all tumour-suppressor functions. The p53 protein is a major tumour suppressor. The gene that encodes it (TP53) is mutated in about half of human cancers, and most remaining tumours find other ways to inactivate the p53 pathway1. IS - 7254 JF - Nature SN - 0028-0836 EP - 467 TI - Cancer: Three birds with one stone PB - Nature Publishing Group VL - 460 SP - 466 KW - biomedical KW - cancer KW - p53 AU - Toledo, Franck AU - Bardot, Boris PY - 2009/07/22/ UR - http://dx.doi.org/10.1038/460466a ER -